294 GUY A. VOISIN AND RADSLAV KINSKY 



on the abdomen and thorax of the newborn. During the first 

 week after birth, parental cannibahsm caused the complete loss of 

 1 8 litters, amounting to 8i newborns among which 69 had been 

 injected. 



D. Facilitation of the newborns 



Appropriate dilutions of the presumed enhancing CBA sera 

 were injected intravenously into the A newborns. Identical dilu- 

 tions of normal CBA sera were injected in a similar way in other 

 A newborns of the same litters. The doses of serum injected were 

 evaluated in cubic millimetres of pure serum; they usually varied 

 from o- 20 mm.^ to i • 00 mm.^. Additional newborns of the same 

 litters received nothing and served as normal controls. For 

 reasons of technical convenience, the CBA sera (either enhancing 

 or normal) were mixed with the CBA spleen cells before being 

 injected into A newborns, hi some experiments one to three 

 additional injections of CBA sera (either enhancing or normal) 

 were performed on the animals within the first two weeks of the 

 animal's life using the intraperitoneal route. 



In summary, each litter of A newborns was divided into three 

 parts : the first group received CBA spleen cells plus CBA enhanc- 

 ing serum; the second group received the same amount of the 

 same preparation of CBA spleen cells plus CBA normal serum; 

 the third group received either nothing or physiological saline at 

 the same volume, and served as normal controls. 



E. Occurrence of runting 



Occurrence of runting was evaluated by regular weighing of 

 all the animals in all the litters on days 7, 10, 14, 21, 28 and 35 

 after birth. Weight curves were estabhshed for each particular 

 experimental situation. The intensity of the homologous syn- 

 drome was also noted according to the general condition (diar- 

 rhoea, alopecia, asthenia, etc.). 



