SUBJECT INDEX 



425 



Tolerance, 



and graft-versus-host reaction, 404- 



405, 406 

 and lymphoid cells, 152 

 and preimmunization, 206 

 and runting, 287 

 antigenic strength in, 340 

 due to injection of lymphocytes, 



251-252, 265 

 effect of amethopterin, 376-377 

 effect of cortisone, 152-153 

 importance of dose, 150, 155-156, 



158-159, 161-162, 210 

 in adults, 139-140 

 increase in after protection against 



runt disease, 313-316 

 induction of, competitive replace- 

 ment, 331 



in Wistar->Y59 strains, 331-333 

 in embryos, 404, 406 

 in parabiosis, 210, 328-349 



immune status following break- 

 down, 335-336, 339 



increase due to preimmunization, 

 336-337, 340 



specificity and degree, 333-335 

 in pregnancy, 119, 124, 133, 135- 



136 

 in relation to age, 138-162 

 mediated by foetal liver cells, 253, 



257, 267-268 

 neutral period, 160, 161-162 

 of Hving cells, 343 

 produced by irradiated spleen cells, 



41, 42, 43 

 produced by red cells, 40-41 

 relationship with enhancement, 



343-348 

 relation with paralysis, 155, 160 

 relation with runt disease, 343-348 

 replacement in, 341 

 role of thymus in, 3 84-403 

 specific acquired, tests for, 295-296 

 time of development, 378 



Transfer factor, and delayed bacterial 

 sensitivity, 272-274 

 and homograft sensitivity, 274 

 properties of, 273, 283 



Transplantation, of embryonic tissue, 

 120-124, 130 

 role of lymphocytes, 260 



Transplantation antigens, 6-24, 25-35 

 composition of, 1 1 

 effect of electrolytes on, 8-10 

 effect of epidermal cell injection, 14 

 effect of hpid solvents, 14-16 

 effect on haemagglutinin produc- 

 tion, 26 

 escape from grafts, 98, 109 

 importance of structure, 83-84 

 inactivation by connective tissue, 



115 



in foetus, 11 8-1 19 



inhibition of haemagglutination 

 reaction by, 30-32 



in liver, 3 8 



on red cells, 39-40 



preimmunization with, 186, 187 



production of, 26-27 



route of injection, 12-14, 20, 21, 23 



solubihty and solubiHzation of, 8-14 



specific differences of, 63 



specificity of, 45 



thermostabihty of, 16-18 

 Transplantation disease, see Runt 



disease 

 Transplantation immunity, in relation 

 to age, 138-162 



role of thymus, 384-403 

 Transplantation isoantigens, and en- 

 hancement, 72 

 Triton, inactivating effect of, 22 

 Triton 100, solubiHty of antigen in, 1 1 

 Triton-soluble hpoprotein, 74-85 



antigenic activity of, 76-77 



chemical composition of, 79-80 



effect of enzymes on, 81, 82, 87 



extraction of, 74-75 



