56. BLOOD GASES, VARIABLES, FACTORS, AND CONSTANTS: MAN 

 The values from which this table has been synthesized are in many instances derived by calculation from basic as- 

 sumptions, factors, and constants, and do not have the same validity as measured values. Those for females arc in 

 general less well-founded than those for males. A = arterial blood, V = mixed venous blood. 



/I/ 100 ml RBC in contact with plasma, and 100 ml plasma in contact with RBC. /2/ O2 capacity = g Hb x 1.36. 

 This factor based on hemoglobin Fe content of 0.339%. /3/ Assumed to be equal to the value for males. /4/ ml O2 

 dissolved in 100 ml human RBC = 100 x 0.0258 x O2 pressure/760; ml O2 dissolved in 100 ml horse plasma = 100 x 

 0.02089 x O2 pressure/760. /5/ Plasma CO2 = "f" x blood CO2; "f" depends upon pH, O2 capacity, and Hb02 satura- 

 tion per cent, lb/ Arterio-venous CO2 difference calculated as A-V O2 difference x standard resting respiratory 

 quotient of 0.82. /7/ ml CO2 (including H2CO3) dissolved in 100 ml RBC = 0.4399 x 100 x CO2 pressure/760. For 

 plasma, substitute 0.5311 instead of 0.4399. 18/ The values of the factor "c" are provisional, as other factors under- 

 lying it have not in every instance been determined for human blood. Combined CO2 x "c" = carbamino CO2 in 100 ml 

 of red blood corpuscles or plasma. For cells, "c" is calculated from K'/Kgarbamino '" 0-315 for Hb02, 0.11 for 

 reduced Hb) and the mEq of Hb (= 2.05 x 20.0 mM Hb for male arterial cells, 2.08 x 20.0 for female arterial cells, 

 1.99 X 14.7 and 1.55 x 5.3 for male venous cells, 2.02 x 14.9 and 1.57 x 5.1 for female venous cells), and for plasma, 

 "c" is calculated from K'/Kcarbamino (' l-^) ^"'^ 'he mEq of plasma proteinate(= 17.0). /9/ ml N2 dissolved in 

 100 ml RBC = 0.0146 x 100 x N2 pressure/760. For plasma, substitute 0.0117 for 0.0146. 



Contributors : (a) Barron, D. H., (b) Bing, R. J., (c) Com roe, J. H., Jr. (d) Cournand, A., (e) Drabkin, D. L., 

 (f) Hickam, J. B., (g) Kirk, J. E., (h) Lambertsen. C. J., and Kough, R. H., (i) Otis, A. B., (j) Penrod, K. E., 

 (k) Singer, R. B., (1) Singer, R. B., and Hastings, A. B., (m) Van Slyke, D. D., (n) Wood, E. 



Ref e renc e: Albrilton, E. C "Standard Values in Blood," Philadelphia: W. B. Saunders Co., 1952 (adapted from 

 Table 94). 



56 



