10. PARTITION COEFFICIENTS OF VARIOUS GASES AT 37-38°C 



Adapted from Kety, S. S., Pharm. Rev., Bait. 3:5. 1951. 



Partition coefficient = the ratio at equilibrium in which a given substance (gas) distributes itself between two or 

 more different solvents. 



Contributors : Bartels, H., and Opitz, E. 



References : [l] Widmark, E. M., Acta med. scand. 52:87, 1919. 



[2] Grollman, A., J. Biol. Chem. 82:317. 1929. 

 and Chapman. C. B., Fed. Proc. 9:124, 1950. (4] Lawrence. J. H., Loomis, W. F., Tobias, 

 F. H., J. Physiol. j05: 197, 1946.15] Moore, B.. and Roaf, H. F., Proc. Roy. Soc. Lond. 

 Nicloux, M., and Yovanovitch, A.. C. rend. Soc. bid. 91: 1285, 1924. [7] Tissot, M. J., ibid 

 McCoUum, J. L., J. Pharm. Exp. Ther. 40:305. 1930. "T?] Orcutt, F. S., and Seevers, M. H., 

 (10) Ruigh, W. L., Proc. Soc. Exp. Biol. 40:608, 1939. (11) Harmel, M. H., Pharm. Rev., 

 Haggard, H. W., J. Biol. Chem. ^5: 1 31 . 1923. [13] Haggard, H. W., ibid 59:771, 1924. 

 and Schilling, C. W.. ibid 113:649. 1936. [15] Van Slyke, D. D., Dillon, R. T., and 



( 3] Taylor. H. L. 

 C. A., and Turpin 

 73:382, 1904. [6] 

 60:195, 1906. [8] 

 ibid 59:206, 1937. 

 Bait. 2:1. 1951. ( 12 



[ 14] Hawkins, J. A. 



Margaria, R., ibidj^:571, 1934. [16] Campbell, J. A., and Hill, L., Quart. J. Exp. Physiol., Lond. 23:219. 

 1933. [17] Campbell, J. A., and Hill, L., J. Physiol. 21:309, 1931. [18] Tobias, C. A., Jones, H. D.. 

 Lawrence, J. H., and Hamilton, J. G., J. Clin. Invest. 28:1 375, 1949. [ 19] Siebeck, R., Skand. Arch. Physiol., 

 Berl. 21:368, 1909. [20] Kety, S. S., Harmel, M. H., Broomell, H. T.. and Rhode, C. B., J. Biol. Chem. 

 r73:487, 1948. [21] Eckenhoff, J. E., Hafkenschiel, J. H., Harmel, M. H., Goodale, W. T., Lubin, M., Bing, 

 R. J., and Kety, S. S., Am. J. Physiol. 252:356, 1948. 



1 1. DEPRESSION OF Oz AND COz SOLUBILITY BY VARIOUS SALTS IN WATER 



Aq = solubility depression per unit M concentration of salt. Values of A are for salt concentrations up to 0.3 M. 



III Corrections for physiological substitute- solutions. 



Contributors : Bartels, H., and Opitz, E. 



References : [ Column B] Sendroy, J., Jr., Dillon. R. T.. and Van Slyke, D. D., J. Biol. Chem. 105:597, 1934. 

 [ Column C] Van Slyke, D. D., Sendroy, J., Jr., Hastings, A. B., and Neill, J. M., ibid 78:765. 1928. 



