CARBON DIOXIDE (ALVEOLAR) 

 in acidosis and alltalosis, 267 

 added dead space values, 266 

 in basal respiration, 44, 45 



breathing various CO2 concentrations, 163, 164 

 effect of exercise, 155, 263-265 

 during hyperventilation, 263 

 pressure, 392 



at altitude, 151-155 

 in basal state, 45 



breathing various CO2 concentrations, 163, 164 

 breathing O2 concentrations, 170, 174 

 effect of combined anoxia and hypercapnia, 158, 159* 

 physiological variability, 91, 92 

 respiratory dead space for, 49 

 threshhold, 163, 164 

 CARBON DIOXIDE (BLOOD), 56, 57 (See also ACID 

 BASE) 

 absorption as function of PCO2 (animals), 64, 65 

 A-V differences (mammals), 56, 58, 314 

 equations for calculating absorption, 64, 65 

 pressure, 56, 57, 392 

 at altitude, 151, 156 

 effect of anoxia, 156, 157 

 breathing various CO2 concentrations (mammals), 



163, 173 

 effect of decompression (dog), 175 

 effect of drugs (mammals), 178-199 

 effect of temperature changes (mammals), 62* 

 in fetal and maternal blood, 83, 84 

 during pulmonary fibrosis, 268 

 in relation to cerebral respiration (dog), 313 

 values for constructing O^ dissociation curves, 

 66-71 (See also OXYGEN DISSOCIATION) 

 CARBONIC ACID 



calculation of serum pK' (mammals), 63* 

 dissociation constants (mammals), 63 

 dissociation formula, 86 

 CARBON MONOXIDE 



diffusion coefficients, 11 



effect on pulmonary function (dog), 182, 183 

 permeation coefficients, 11 

 solubility coefficients, 6 

 CAROTID- BODY CHEMORECEPTORS, respiratory 



action of drugs influencing (mammals), 200 

 CEREBRAL BLOOD FLOW, O^ consumption, and 



vascular resistance (mammals). 312 

 CEREBRAL RESPIRATION (dog), 313, 314 

 CHEMORECEPTORS, CAROTID- BODY: respiratory 



action of drugs influencing (mammals), 200 

 CHLORIDE ION, plasma constituent (vertebrates). 93, 94 

 CHLOROFORM 



partition coefficients, 5 

 respiratory action, 200, 204, 250 

 CHLOROPLASTS, pigments of, 124, 125 

 CIRCULATION, PULMONARY (mammals), 54, 55 



summary of values, 392 

 COEFFICIENTS of various gases 

 diffusion, 3, 10, 11 

 partition, 5 

 permeation, 10, 11 

 solubility, 6-9. 56 

 COMPLIANCE, 392 



lung-thorax system (mammals), 135 

 pulmonary (vertebrates), 135-137 

 CORONARY REFLEX, 139 

 COR PULMONALE (mammals), 54, 55 

 CORPUSCLES (See ERYTHROCYTE(S)! RBC) 

 CUIRASS METHOD, artificial respiration, 142 



CYCLOPROPANE 



partition coefficients, 5 



respiratory action, 201 

 CYTOCHROMES 



animals and higher plants, 124, 125 



bacterial. 128. 129 



iron-porphyrin pigments, 115-117 



DALTON'S LAW, 4 



DEAD SPACE. RESPIRATORY 



added, effect on respired air. 266 



anatomic (mammals), 46-48*, 49, 50*, 51 



during CO2 hyperpnea, 47 



effect of breathholding, 48, 49 



effect of exercise, 47 



equations, 391 



and functional residual capacity (dog), 48* 



in pathological conditions, 51 



physiologic (mammals), 28, 46-48*. 49. 50*. 51, 392 



and tidal volume (mammals), 47, 48*, 50*, 51 



for various gases, 49 

 DECOMPRESSION 



effect on blood gases (dog), 175 



effect on blood pressure, respiratory rate and pulse 

 rate (dog), 176* 



effect on internal pressures (dog), 177 

 DEFLATION RECEPTORS, PULMONARY: respiratory 



action of drugs influencing (mammals), 201 

 DENSITY, AIR, 2, 3 



DIFFUSION, ALVEOLAR-CAPILLARY, 53* 

 DIFFUSION CAPACITY of lungs, 52 

 DIFFUSION COEFFICIENTS of gases. 3. 10. II 

 DIPYRROLIC COMPOUNDS, characteristics. 123 

 DISEASE (See also specific disease) 



comparative pathology of the pneumoconioses. 270 



effect on cerebral blood flow and O2 consumption 

 (mammals). 312 



effect on lung connpliance. 137 



effect on pulmonary circulation (mammals), 54. 55 



effect on pulmonary function, 268 



respiratory dead space during, 51 

 DISSOCIATION CONSTANTS, H2CO3 (mammals). 63 

 DISSOCIATION, Oz (See OXYGEN DISSOCIATION) 

 DIVINYL ETHER 



partition coefficients, 5 



respiratory action. 200 

 DRUGS 



effects of, 178-252 



effect on A-V O2 and CO2 differences (mammals), 58 



effect on cerebral blood flow and O2 consumption 

 (mammals), 312 



effect on pulmonary circulation (mammals), 54 



effect on pulmonary function (mammals), 178-199 



influencing afferent end-organs, respiratory action 

 (mammals), 200. 201 

 DRUGS ACTING ON THE BRONCHI (vertebrates), 202-252 



aerosols, gases and vapors, 250-252 



antagonists and potentiators of, 226-248, 252 



direct action of, 202-214, 250, 251 



pA^ values for antagonists of, 249 



sympathomimetic amines, 215-225, 251 

 DYSPNEA, physiology of, 274 



EISENMENGER SYNDROME, effect on pulmonary 

 circulation (mammals), 54, 55 



397 



