748 



HANDBOOK OF PHYSIOLOGY 



CIRCULATION I 



as indicator of autonomic innervation, 

 388 



cardiac output and, 542-543, 548 



change, with no change in aortic re- 

 sistance, 496-497 



ECG intervals and, 370 



ectopic beats, ECG of, 398 



factors controlling, 396 



homeometric autoregulation and, 497 



paroxysms, 396-397 



physiological arrhythmias, index of, 



397 

 potassium flux and, 1 60 

 Q-T interval and, 316, 382 

 reflex changes, 524 

 respiration and, 397 

 response to environment, 539 

 sodium flux and, 160 

 tachycardias, 396-397 

 Heart sounds 



alterations in electrical activity and, 



707 

 areas of preferential transmission, 697 

 atrioventricular valve, 7 1 2 



stenosis and, 719 

 cardiac cycle and, 698 

 constrictive pericarditis and, 7 1 1 

 definition, 696 

 diastolic knock, 71 1 



definition, 71 1 

 disease states and, 709 

 ejection sounds, hemodynamics of, 



713-714 

 electrocardiogram and, 703 

 factors affecting, 697 

 first, 699 



heart block and, 707 



in rheumatic fever, 7 1 o 



valvular disease, and, 709 

 fourth, 701 



genesis of, 701 

 gallop, 710 



diagnostic \alue, 7 1 1 



mechanism of, 711 



types, 7 1 I 

 genesis, 696 

 heart block and, 707 

 in diagnosis of congenital defects, 423 

 in valvular insufficiency, 699 

 intravascular pressures and, 698 

 mechanical events in heart and, 702 

 mitral commissurotomy, 710 

 pericardial friction rub, 714 

 physical basis for, 696 

 physical considerations, 682 

 physiology of, 682 

 P-R interval and, 708 

 recorded internally and externally, 682 

 respiration and, 705 

 rheumatic fever and, 709-7 1 o 

 second, 700 



expiration and, 707 



inspiration and, 706 

 semilunar \'alve, 710 

 stenosis and, 710 



summation gallop, definition, 711 

 third, 700 



source, 700 

 transmission, 697 



in heart, 730 

 valve motion, mechanical activity 



and, 701 

 iee alio Heart murmurs; Cardiac 



acoustics ; Phonocardiography 

 Helmholz, H. F., Jr. 



Physiologic consequences of con- 

 genital heart disease, 417-487 

 Hematocrit 

 arterial, 33 

 central 



in dog, 33 



in man, 31 



in monkey, 32 

 dynamic, 145 

 errors in computing, 30 

 in drawn blood, 29 

 locEil circulatory, 32-34 



lung, 33 



mean circulatory, 30-32 



mean corpuscular volume and, 30 



measurement of, 29 



plasma substitutes and, 71, 74, 78, 79 



renal, 33 



tissue 



central, 32-33 

 dog, 32 

 monkey, 32 

 venous 



blood vokmie calculation and, 596 

 dog, 32 

 man, 31 

 monkey, 32 

 significance, 596-597 

 Hematopoietic activity 



blood volume and, 60 

 Hemodromograph 



diagram, 553 

 Hemoglobin 



O; dissociation curves, 203 

 plasma substitutes and, 74 

 Hemoreflector 



description, 425 

 Hemorrhage 



blood volume and, 57 

 Hemostasis 



plasma substitutes and, 71 

 Heterometric autoregulation: see Heart; 



Atria; Ventricles 

 Hexamethonium 



cardiac output and, 664 

 Hexokinase 

 in heart, 228 

 in skeletal muscle, 228 



Hexosediphosphate phosphatase 



in heart muscle, 207 

 Homeometric autoregulation: see Heart; 



Atria; Ventricles 

 Hooke's law 



definition, 3 



illustration, 92 

 Hormones 



blood volume and, 54 

 Horse 



blood \olume, 52 



cardiac output in, 568 



electrocardiographic data, 402 

 Hydrogen 



diagnosis of congenital cardiac de- 

 fects and, 428 

 Hydrogen transport 



in cardiac muscle, 2 1 2 

 Hyperpnea 



chronic hypoxia and, 479 

 Hyperthyoidism 



cardiac metabolism in, 224-225 

 Hypoglycemic shock 



ECG and, 390 

 Hypophysectomy 



blood \olume and, 54 

 Hypothermia 



cardiac glycogen and, 210 



electrocardiograph and, 392, 401 



ventricular function curves and, 492 

 Hypothyroidism 



blood volume and, 54 

 Hypoxemia 



cardiac output and, 477 

 Hypoxia 



cardiac action potential and, 317 



cardiac metabolism in, 222-223 



chronic, hyperpnea and, 479 



circulatory adaptation to, 477 



electrocardiograph and, 387 



in cardiac disease, 221 

 Hysteresis 



definition, 1 1 1 



Impedance 



cardiac, veratrum alkaloids and, 181 

 input 



calculated from damping constants, 



■25 

 length and in closed tube, 124 

 obser\ed for given frequency. 125 



mechanical, concept, 133-134 

 Indicator-dilution curves 



aortic regurgitation and, 435 



arterial 



cardiac output and, 431,574 

 congenital heart defects and, 431 

 definition, 429 

 normal, 429, 574 



atrial septal defect and, 463 



cuvette-oximeter characteristics and, 



430 



