INDEX 



7: 



Myoglobin 



aerobic metabolism and, 204 



in skeletal muscle, 229 



of heart muscle, 203-204, 229 



oxygen dissociation curve, 203 

 Myosin 



arrangement in cardiac muscle, 201 



in muscle contraction, 219 



of cardiac muscle, 2 1 6 



pathological changes, 225 



NEFA: see Fatty acids 



Nephrosis 



plasma substitutes and, 80 



Nernst equation 



bioelectrical potentials and, 1 59 

 ionic equilibrium potential, 242 



Nerve 



anodal break excitation, 257 

 quantitative description of behavior, 



254 



refractory period, equations for, 258 



threshold excitation, 257 

 Newborn infant 



pulmonary hypertension in, 439 

 Nicotinic acid 



in heart, 228 



in skeletal muscle, 228 

 Norepinephrine 



aortic regurgitation and, 660 



effect in isolated heart, 500 



in homeometric autoregulation of 

 ventricle, 499 



left atrial pulse pressure and, 654 



LVED pressure and, 492 



stroke work and power and, 492 



T wave and, 389 



ventricular function ciuves and, 492, 

 501 

 Nutrition 



blood volume and, 56 



substrate utilization in heart and, 221 



Ohm's law 



as applied to vascular resistance, 428 

 Oligemia 



plasma substitutes and, 78 

 Olson, R, E. 



Physiology of cardiac muscle, 199-235 

 Oscillography 



in phonocardiography, 688 

 Ouabain 



ATPase activity, 183 



electrocardiograph and, 359 

 Oxidative phosphorylation 



in cardiac muscle, 2 1 2 

 Oximetry 



description, 426 

 Oxygen consumption 



heart, 229 



quinidine and, 180 



skeletal muscle, 229 



Oxygen saturation ; see Arterial oxygen 



saturation 

 Oxypolygelatin 



as plasma expander, 64 



P wave 



excitation pattern of, 349 



length, heart rate and, 370 



mitral, 349, 368 



normal characteristics, 367 



pulmonary, 349 



recorded at various sites, 294 



theory, 349-354 



see also Electrocardiogram 

 Pantothenic acid 



in heart, 228 



in skeletal muscle, 228 

 Parallel systems 



definition, 621 

 Parasystolic rhythm 



definition, 393 

 Paroxysmal tachycardia 



aconitine and, 395 

 Patent ductus arteriosus 



characterization of, 418 



closure, after birth, 439 



drugs and, 726 



heart murmurs and, 721 



hemodynamic changes due to, 452 



phonocardiogram of, 729 



pulmonary hypertension and, 458 

 Pfo., ; see Carbon dioxide 

 Pectin 



antigenic properties, 6g 



as plasma expander, 64 



blood constituents, 74 



fate of, 66 

 Pentalogy of Fallot 



definition, 420 

 Pentose phosphate shunt 



in cardiac muscle, 208 

 Pericardial disease 



heart sounds and, 7 1 1 

 Period 



definition, 398 

 Persistent common atrioventricular canal 

 description, 468 



hemodynamic findings, 468 



pulmonary and systemic flows in, 469 



ratio of pulmonary and systemic vascu- 

 lar resistance to net intracardiac 

 shunt, 470 

 Persistent truncus arteriosus 



characterization of, 418 

 Pheochromocytoma 



T wave and, 389 

 Phonocardiogram 



instrumental frequency in, 689 



of atrial septal defect, 7 1 2 



of late systolic murmur, 687 



of mitral stenosis, 690 



of musical inurmurs, 690 



of tricuspid insufficiency, 728 

 spectral, in mitral stenosis, 691 

 Phonocardiography 



abnormal heart sounds and, 710 



amplification, 685 



areas for recording, 692 



artifacts, 691-692 



circuit for low-frequency attenuation, 



685 

 current problems in, 732 

 display of, 687, 688-691 

 ejection sounds, 7 1 3 

 equalization, 685-688 

 filter characteristics, 687 

 filters in, 685 



spectral, 686 

 filtration, 685-688 

 frequency responses of various systems, 



686 

 intensity calibration, 693 

 intracardiac, 693, 729-732 



artifacts, 73 1 

 low-frequency attenuation, 685-688 

 microphone operation, 684 

 multifilter system, 686 

 muiTnurs, 714-724 



of nonvalvular origin, 720 

 nature of, 682-683 

 physical basis, 696-698 

 physical considerations, 682 

 physiologic data for correlations, 691 

 physiological basis, 698-729 

 physiology of, 682 

 practical aspects, 691 

 recording 



direct, 692 



direct and indirect, 684 



spectral, 689 

 sound spectograph for, 688 

 special techniques, 692-694 

 storage, 692 

 systolic clicks and, 713 

 systolic gallops and, 7 1 3 

 transducers, 684-685 



classification, 684 

 see also Cardiac acoustics; Heart mur- 

 murs 

 Phosphoenolpyruvate 



Utter-Ochoa pathway, 207 

 6-Phosphogluconate dehydrogenase 

 in heart, 228 

 in skeletal muscle, 228 

 Phosphorus 



radioactive, as cell label, 41 

 Pliosphotransferase 



in cardiac muscle, 214 

 Pituitary gland 



perfusion rate, 642 

 Plasma 



anatomical limits of compartment, 35- 



36 

 as expander, 64 



