14 Discussion 



diuresis? Did it increase the ratio of water to solutes in the urine, or did 

 it increase the solute output? 



Adolph: Adrenaline diuresis in infant rats does involve more solute 

 output than the water diuresis, but adrenaline diuresis is a water 

 diuresis in that the urine is very dilute. I do not think you could blame 

 all the adrenaline diuresis on the solute output itself. 



With regard to immaturity and whether it takes experience for an 

 animal to have a diuresis, we can point to the fact that adrenaline diure- 

 sis has no experience-factor. We have tried to see whether we could get 

 more water diuresis in the infant animal by subjecting it to water loads 

 on successive days. There is a considerable variation in the amount of 

 water excretion which is produced, and we are unable to say that there 

 is any significant change due to previous experience with water. Our 

 provisional conclusion is that there is no adaptation apparent in the 

 animal subjected to repeated water-loading. 



