Effect of Age on the Body's Tolerance 147 



dextrose, 40 m-equiv. of sodium, 35 m-equiv. of potassium, 

 40 m-equiv. of chloride, 20 m-equiv. of lactate and 15 m-equiv. 

 of phosphate (Talbot, Crawford and Butler, 1953; Talbot et 

 al., 1955). The first set of subjects received their allotment by 

 mouth in an essentially continuous (hourly dose) manner, the 



{ 



\l {i 



400 



K 



mEq /m2/24» 200 





 400 

 CI 

 fnEq/m2/24» 200 



SI i 



A\ 



iixii 



10 

 YEARS 



20 



Fig. 6. Relations between rates of output observed for 

 subjects on various regimens shown in Fig. 5 (right- 

 hand section) and physiological ranges of excretory capa- 

 city shown in Fig. 2 (left-hand section). The solid 

 black circles indicate the average and the vertical bars 

 traversing them the ranges in output rate noted for the 

 individual subjects per the scales along the left-hand 

 ordinate. (From Neyzi, Bailey and Talbot, 1958). 



second set at twice the rate for 12 hours each day and the 

 third set at quadruple the rate for six hours out of every 24. 

 As indicated by the length of the vertical lines at the right of 

 Fig. 6, those on the 24-hour regimen utilized but a small 

 fraction of their physiological ranges of excretory capacity in 

 accomplishing metabolic homeostasis. By contrast, those on 



