Hormones and Homeostatic Mechanisms 



173 



and 33-day-old controls. As this is not the case and as 

 in the younger animals increased natriuresis is mainly due 

 to increased concentration at the time of maximum water 



23 days 



I H2O 

 100 



— water controls 



— water cortisone 

 -- sodium controls 



— sodium cortisone 



mE/1 Na 

 100 



33 days 



Fig. 3. The effect of cortisone (0-25 mg./lOO g. body wt./day) on the 



course of the excretion of a water load and the concentration of sodium 



in the excreted urine in infant rats aged 23 and 33 days. 



diuresis, relations are evidently more complex. This is also 

 borne out by the fact that the effect of cortisone in the younger 

 group is variably dependent on the dose used. 



