276 



Z. Fejfar 



The elevation of renal blood flow was effected in the great 

 majority by a decrease in postglomerular resistance, the 

 filtration fraction diminishing 17 times and increasing in only 

 three instances. 



The increase in chloride clearance was of the same order as 



1000 



900 



eoo 



TOO- 

 600 

 500 

 iOO 



1/ rn rjr^.., or rt PT rt^.. —SS. 



CO Ctp^ RF Ct,„, FF Ctct' 



Ct.r 



*m 



► 55" ♦^S *27 -16 *2B *!57 



Fig. 3. Percentage nocturnal changes in urine flow 

 (V), cardiac output (CO), renal plasma flow (ClpAg), 

 renal fraction of cardiac output (RF), glomerular 

 filtration rate (Cljn), filtration fraction (FF), 

 chloride clearance (Clcr) and in the ratio of chloride 



clearance to glomerular filtration rate ( -^^ — I • The 



mean percentage change (^) and range (□) in 14 

 patients with heart failure are presented. The 

 lower urine output was taken as 100 %. 



the elevation of urine volume. The mean increase was 215 

 per cent, range 2 to 910 per cent. The ratio of chloride clear- 

 ance to glomerular filtration rate rose on an average by 157 

 per cent (range —17-6 to +530 per cent). 



