278 



Z. Fejfar 



Himbert and co-workers (1954), Cort (19556), Cort and 

 Fencl (1957), and others. 



Doyle and Merrill (1957) studied renal function in 18 

 patients with congestive failure in a supine position and tilted 

 in a passive erect posture. The changes were qualitatively 

 similar to those in normal subjects. There was a further 

 depression of renal plasma flow, glomerular filtration rate and 

 also a decreased urine flow and a fall in the excretion of the 



Fig. 4. Relationship of the amount of the chloride filtered (Pd X Clinul.) and 



^ X 100 ) in individual subjects at high and low urine 



Values in individual subjects are connected with dotted lines. 

 N — normal control subjects ; C — patients with heart disease. See text for 



details. 



reabsorbed ( ^ ^, 



VPci X Clinul 

 flows 



electrolytes. In accord with our previous findings, with 

 nocturia the decreased urine flow in the erect posture was 

 closely correlated with changes in renal plasma flow. There 

 was, on the other hand, a very poor correlation between 

 changes in glomerular filtration rate and sodium excretion. 



In these observations there was an indirect relationship 

 between the tubular reabsorption of electrolytes and water 

 and renal blood flow. The tubular reabsorption increased 

 when renal blood flow fell and vice versa. 



This finding does not characterize congestive failure alone. 



