Historical Introduction -> 



throughout Europe ; in it he collected together the ideas of the time 

 and examined them critically and sceptically. This scepticism 

 threw doubt on the experimental basis of the current ideas in 

 physiology and suggested new experimental and theoretical ap- 

 proaches. The modern reader of this remarkable book is struck by 



Tub. II 



* 



Fig. i.i (b). Cannulae and other instruments used by de Graaf. 

 (Regner de Graaf, De succo pancreatico, 1677.) 



the similarity of its spirit to that of the comparably influential 

 General physiology by Bayliss (1924). Miiller was greatly interested 

 in the relationship of the gland cells to their secretion. He recog- 

 nized the difficulties imposed by the unidirectional character of 

 the secretory process, and was the first to realize that efferent 

 nerves to secretory glands might be secretomotor. He produced 



