RAREFYING DISEASE OF THE SKELETON 



m 



40' 



Fig. 6E. Anteroposterior view of the pelvis showing accentuation of the 

 trabeculae of the internal architecture, and decrease in the density of the lateral 

 cortex of the neck of the femur in the case shown in Figs. 6A to 6D. 



demonstrated the established fact that strontium is not reabsorbed 

 as efficiently as calcium by the kidney tubules (Fig. 10). The rela- 

 tive values of the exchangeable pool and calcium excretion rate, 

 as shown in Table I, are calculated on the basis of urinary clearance 

 of strontium, and therefore are not absolute values but can be used 

 to compare one case with another. Our impression was that the size 

 of the exchangeable calcium pool (on the basis of the osteogram) 

 was the same during the entire period of treatment, but the accre- 

 tion rate was greater with polysaccharide than with human growth 

 hormone. Calcium balance was unchanged, however, and it is neces- 

 sary to assume that the higher rate of accretion was associated with 

 a higher rate of resorption. This is reflected in the urinary excretion 

 curves of Fig. 10. The dailv loss of Sr^^ in the urine accompanying 



