BONE DESTRUCTION BY MtLTINUCLEATED GIANT CELLS 



5^21 



Group 3 



This group of rachitic decalcified scapulae was a control on group 

 2 and was included to ensure that omitting decalcification was not 

 responsible for the inability of the giant cells to attack osteoid. Giant 

 cells appeared around the implants 2 weeks after implantation and 

 were observed in increasing numbers with the passage of time. 

 It was of course impossible to distinguish with anv certainty rachitic 

 osteoid from decalcified bone, but osteoclasis proceeded with the 

 usual vigor. 



i 



■ — . 



Co 



<o 

 Co 



k 

 :»: 



^^ 



+ 30 



+ 25 - 



+ 20 - 



+ 15 



+ 10 - 



+ 5 



-5 



-10 





Fig. 3. The loss of wet weight of devitalized bone implants. There were 

 7 animals in each group. The bars show the means plus and minus the standard 

 deviation. 



