20 



Resorption without Osteoclasts (Osteolysis) 



LEONARD F. BELANGER. Department of Histology and Em bryology, 

 Faculty of Medicine. University of Ottawa, Ottawa, Canada 



JACQUES ROBICHON, Department of Histology and Embryology. 

 Faculty of Medicine. University of Ottawa, Ottawa, Canada 



B. B. MIGICOVSKY. Animal Research Institute. Research Branch. 

 Canada Department of Agriculture. Ottawa. Canada 



D. HAROLD CORP. Department of Physiology. Faculty of Medicine. 

 X niversity of British Columbia. Vancouver. Canada 



JACQUES VINCENT. Department of Anatomy. Iniversite Lovanium. 

 Leopoldville, Congo 



REMOVAL of minerals from the deeper regions of bone tissue has 

 been postulated on the basis of morphological ( Zawisch-Ossenitz, 

 1927; Heller-Steinberg, 1951; Ruth, 1954, 1961) and physiological 

 observations (Talmage and Elliott, 1958; Talmage, 1962). Local 

 changes in the organic matrix such as basophilia ( Zawisch-Ossenitz, 

 1927; Ruth, 1954, 1961) or "depolymerization of the mucopolysac- 

 charides" (Heller-Steinberg, 1951) have been associated with this 

 phenomenon. More recentlv, bands of low density have been de- 

 scribed in alpharadiographs (Belanger and Belanger, 1959) of de- 

 mineralized trabeculae of rachitic (Vincent et ah, 1962) and nor- 

 ethandrolone-treated chicks (Belanger and Migicovskv, 1961). A 

 correlation between mid-trabecular low densitv of the matrix and 

 basophilic staining was also established (Belanger and Migicovskv, 

 1961). 



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