PARATHYROID HORMONE AND RAT CALVARIA METABOLISM 



GLUCOSE 



597 



4 8 



GLUCOSE mM 



Fig. 2. Lactate production by calvaria incubated in vitro. A, the Qj^ in 

 fimoles per gm wet weight with time in the presence and absence of added 

 glucose. B, the variation in Qj^ as /j.moIes/gm/hr. with varying glucose con- 

 centration in both phosphate and bicarbonate media. C, the variation in Q^^ 

 with variation in pH; phosphate medium, glucose 17 mxi. 



bicarbonate ion concentration was 25 niM, phosphate 1.2 niM; in 

 the phosphate medium, phosphate was 16 niM, bicarbonate being 

 absent. Interestingly enough, the medium effect was missing under 

 anaerobic conditions (Table IV), lactate production in both cases 



TABLE IV. The Effect of Medium on Lactate Production 

 (Mean values of six flasks) 



