740 



Osteoclasts — Continued 



phagocytosis, 489, 512, 528 



pinosomes, 501, 506 



precursors, see Osteoclast precursors 



readiness for phagocytosis, 512 



resorbing surface, 451 



resorption, 639 



ribosomes, 499 



ruffled border, 499, 501, 506 



saclike vesicles, 508 



striated border, 498 



structure-function relationships, 497 



succinic dehydrogenase, 614 



summarv, 512 



tissue culture, 511 



trypan blue uptake, 520 



ultrastructure, 497 



vacuoles, 613 

 Osteoclasts versus giant cells, 527 

 Osteocyte canaliculi, 481 

 Osteocyte counts, osteoporosis, 419 

 Osteocvte lacunae, 483 



osteomalacia, 465 

 Osteocvte sheaths, 425 

 Osteocytes, 372, 375 



beryllium intoxication, 522 



dual role, 552 



fluorosis, 552 



glycogen, 487, 489 



glycolytic cvcle, 380 



life expectancy, 397 



mobilization of bone mineral, 379 



normal bone, 486 



osteoblast characteristics, 490 



osteolathyrism, 522 



parathyroid extract, 489 



proteolytic enzvme, 395 



resorption, 639, 640 



resorptive potential, 489, 642 



rickets, 465 



woven bone, 465, 477 

 Osteocytolysis, 416, 425, 438 

 Osteodystrophy, 385 

 Osteogenesis 



active, 472 



nucleolar RNA, 487 



remodeling, 321 

 Osteogenesis imperfecta, 385, 426 



SUBJECT INDEX 



confluent lacunae, 549 



diaphyseal bone, 551 



microradiography, 462 



unremodeled bone, 462 

 Osteogenic complex, 491 

 Osteogenic microenvironment, 491 

 Osteogenic sarcoma, 549 

 Osteogenic surfaces 



parathyroid action, 487 



rib shaft, 483 

 Osteogram, 392, 413 

 Osteoid, 536 



phase contrast photomicrography, 

 481 



PTE-treated animals, 488 



rachitic, 515, 520 

 Osteoid tissue, failure of mineraliza- 

 tion, 465 

 Osteolathyrism, osteocytes, 522 

 Osteolysis, 531, 639 



see also Bone destruction; Bone re- 

 sorption 



collagen, 553 



fluoride, 552 



lathyric seed, 552 



mechanism of, 553 



mucopolysaccharides, 553 



pregnancy, 552 

 Osteolytic action, osteoclasts, 377 

 Osteolytic effects, biochemical mecha- 

 nisms, 589 

 Osteolytic phenomenon, 552 

 Osteomalacia, 385 



osteocyte lacunae, 465 

 Osteons, 372 



active, 395 



biologic half life, 375 



cortical bone, 396 



density, 372 



porosity, 455 



resorption cavities, 457 



reversal cement lines, 399 



sclerotic rings, 456 

 Osteopenia, 424 

 Osteoporosis, 95, 385 



accelerated aging, 417 



adrenal cortical hormones, 428, 432 



adrenalectomy, 429 



