SUBJECT INDEX 



CUona — Continued 



sfationis. 31 



vdfitifica. 30, 33 

 Clionid sponges, 27 



mechanism of boring, 31 



siliceous spicules, 30 

 Clionidae, 29 



Clostridium, collagenase, 680, 685 

 CO. 



dissolution of shell, 55 



production by parathyroid hormone, 

 581 



requirement of caries bacteria, 275 



streptococcal growth, 275 

 Coalescence, bone cells, 489 

 Code information, resorption, 490 

 Codfish spine, 422 

 Colgate-Palmolive Company , 208 

 Collagen 



assay techniques, 684 



basement lamella, 687, 688 



biological life span, 570 



cold, removal, 671 



conversion rate, 676 



cross linking, 668 



cross-striated fibrils, 680 



crystal binding, 503 



dispersed state, 667 



lysis, 680 



metabolic turnover, 664 



net synthesis, 676 



osteolysis, 553 



protective coat, 688 



rate of resorption, 673 



rate of synthesis, 673 



ruffled border area, 501, 510 



solution, 503 



specific activitv, 675 



terrestrial mammals, 674 

 Collagen breakdown, proteolytic en- 

 zymes, 679 

 Collagen degradation 



bone, 424 



collagenolytic enzyme, 679 



irradiation, 424 



resorbing calvaria, 624 

 Collagen digestion, proteolytic en- 

 zvmes, 685 



Collagen fractionation, hypothesis, 668 

 Collagen fractions, 668 



extractable, 673 



guinea pig skin, 679 



insoluble, 674 



isotope data, 674 



rodent skin, 677 



specific activity, 678 

 Collagen gels, reconstituted, 664 

 Collagen metabolism, 663 



metamorphosing tadpoles, 667 



theory, 667 

 Collagen microassay 



radioactivity, 685 



tissue cultures, 682 

 Collagen molecules, 668 

 Collagen pool 



h\'droxyproline, 673 



proline incorporation, 670 

 Collagen protection, ground substance, 



687, 690 

 Collagen remodeling 



collagenase, 679 



summary, 689 

 Collagen removal, bone growth, 664 

 Collagen turnover time, bone, 580 

 Collagenase 



see also CollagenoKtic enzyme 



acid pH range, 680 



bone, 573 



Clostridium, 680 



collagen remodeling, 679 



cysteine inhibition, 685 



dentin caries, 207 



EDTA inhibition, 685 



pH optimum, 685 



tissvie storage, 687 

 Collagenase activity, index, 685 

 Collagenase-like activitv, ultrafiltrable 



hydroxyproline, 572 

 Collagenase production, cell tvpes, 



689 

 Collagenolytic activity 



bone, 664, 680 



proteases, 686 



tissue extracts, 664 

 Collagenolytic enzyme 



see also Collagenase 



