166 



A. PoLiCARD, C. A. Baud, A. Collett, H. Daniel-Moussard, J. C. Marti 



needle-shaped appearance is clearly observed in the cytoplasm, while the other 

 deposits are extracellular and preferably in the basement membrane which is rich in 

 mucopolysaccharides. 



Fig. 3. Nfcdle-shapcd 



gluconate 



With the exception of vacuoles around intracellular deposits, which we did not 

 observe, our electron microscopic results are in agreement with those of Giacomelli 

 et al. (1964) who induced a D hypervitaminosis in rats. In addition, they obtained 

 an electron diffraction pattern of granular deposits which might be interpreted as 

 the pattern of a mixture of apatite and another crystalline phase. 



Injecting mice with parathormone Caulfield and Schrag (1964) obtained 

 numerous needle-shaped intracellular deposits diffracting electrons like apatite. 



