PREFACE 



viding us with all facilities required for our task. The National 

 Health and Medical Research Council of Australia has supported the 

 work of both authors with research grants for a number of years; it 

 has also made a special grant to one of us (J. W. L.) for a period of 

 four months, which allowed him to contribute extensively to several 

 sections of this book, and has provided us with grants for secretarial 

 help. We are indebted to the Trustees of the Estate of the late Sir 

 Henry S. Wellcome for permitting one of us (J. W. L.) to continue 

 his work on this book during his tenure of a Fellowship in England. 

 Mr. J. P. Callaghan, who has been working in this institute as a 

 research worker under a grant from the National Health and Medical 

 Research Council, has contributed Chapter II and has otherwise 

 greatly assisted in writing and checking other chapters. 



We are greatly indebted to Prof. D. Keilin and Prof. F. J. W. 

 Roughton, to Drs. P. George, N. E. Goldsworthy, J. Keilin, D. P. 

 Mellor, M. F. Perutz, W. P. Rogers, R. N. Robertson, and to Mr. H. 

 F. Holden for valuable advice; to Prof. A. J. Canny, Dr. E. B. Durie, 

 J. L. Still and Mr. H. F. Holden for reading parts of the script; to 

 Drs. F. Bodansky and B. I. Horecker for sending unpublished material 

 for quotation; to Mr. W. A. Rawlinson for the original diagram on 

 which Figure 1, Chapter VI, is based; to various authors whose work 

 we have quoted in extenso, particularly Prof. L. Pauling and Prof. 

 W. M. Clark, and to their publishers for permission to use these 

 quotations; and to several authors who have sent us reprints of their 

 publications. 



The work would have been impossible without the loyal support of 

 the members of the staff of the Institute, particularly of my collab- 

 orators, Mr. E. C. Foulkes and J. Falk, who, together with Mr. 

 Callaghan, have read and reread the manuscript and proofs. 



We shall be indebted to our readers for pointing out errors and 

 obscurities, so that they may be corrected in later editions. 



The book will have fulfilled its purpose if it shows to the student 

 and the general reader how much remains to be done in this inter- 

 esting field of biochemistry, and if it opens new aspects to the research 

 worker and inspires him to attack unsolved problems. 



R. Lemberg 

 June, 1949 J- W- Legge 



