590 



XII. HEMOGLOBIN CATABOLISM, II 



biturates, chloral, cinchophen, and thiosinamine also have occasionally been 

 found to cause porphyrinuria. 



The large number of data on the excretion of porphyrins in diseases or 

 after administration of drugs and poisons have been summarized in Tables I 

 and II. It should be noted that so far only coproporphyrin III has been 

 found in normal rabbit urine, while the isomeride type of the coproporphyrin 



TABLE I 



Excretion of Coproporphyrins in Disease and after Administration 



of Drugs and Poisons 



" Human excreta unless specified. f> Mostly in alcoholic cirrhosis or after arsphena- 

 mines. c Not regularly increased. ^^ Not always increased (2^iO,7667). * No ade- 

 quate studies (cf. 603). /Probably a deuteroporphyrin, not coproporphyrin. 



