SUBJECT INDEX 



737 



hemjglobiii icontd.) 



and salicylate, 25S 

 variety of hem/globins, 390, 391, 

 395, 525 

 hemiglobin compounds 

 with azide, 221, 407 

 with cyanide, 219 



absorption spectrum, 226, 228 



(table) 

 and cytochrome oxidase, 220 

 equilibrium, 220 

 reduction of, 216 

 with fluoride, 219 

 with hydrogen peroxide, 221 

 with hydroxide, 218 



absorption spectrum, 218, 228 



(table), 229 

 dissociation, 219, 236, 269 

 magnetochemistry, 219 

 reaction with ammonia, 222 

 reaction with ethanol, 222 

 with hydrosulfide, 221, 269 

 with imidazole, 222 

 with nitric oxide, 221 

 with other anions, 222 

 hemi'globinemia, 518 



by drugs and poisons, 519 

 idiopathic, 519, 522 

 hemoglobin formation, 389-394, 519 

 by aromatic amino and nitrocom- 

 pounds, 519 

 by autoxidation. See Hemoglobin. 

 by bacteria, 480 

 and choleglobin formation, 476, 477, 



480 fJ. 

 in erythrocytes, 518 

 and erythrocyte destruction, 522 

 hydrogen donors in, 391, 393, 480 

 hydrogen peroxide and catalase in, 



392, 417, 481, 520, 521 

 kinetics, 285, 393 

 by methylene blue, 391, 521 

 by nitrite, 389 

 hemoglobin, 215 



absorption spectrum, 226, 228 (table) 

 autoxidation, 388, 392 

 bond type, 215 

 compounds. See below, 

 dissociation constants, 236 ff., 237 



(table), 276 

 iron, removal from, 230 

 linkage imidazole-iron in, 233 ff. 

 and methylene blue, 391 



hemoglobin (could.) 



and phenylhydroxylamine, 390 

 reactivity of freshly reduced, 286 

 hemoglobin compounds. See also 

 Ca rboxyhem oglobin , Oxyhemoglo- 

 bin. 

 with carbylamines, 217 

 with cyanide, 216 

 with hydrogen peroxide, 392, 476 

 with nitric oxide, 216, 228 (table) 

 with nitrosobenzene, 217, 390, 520 

 Hemolysis, 532 



Bergenhem-Fahraeus me<'hanism, 530, 



533, 536 

 and mortality curve of erythrocytes, 



513 

 in newborn, 537 

 by a plasma factor, 533, 536 

 and porphyrin formation, 593, 596 

 by soaps and fatty acids, 533 

 by spleen in hemolytic anemias, 537 

 by tissue factor, 534 

 Hemolytic index, 556 

 Hemopoiesis, 603, 607 ff. See also Anti- 

 perniciou.^ anemia principle. Copper, 

 Erythrocytes, Folic acid. Hemoglobin 

 (anabolism). Pterins. 

 and bile acids, 616 

 and endocrine factors, 620 

 and liver, 611, 616 

 megaloblastic. See Embryo. 

 and oxygen pressure, 625 

 Hemoproteins, 7, 337 



electrometric titrations, 27, 28 

 oxidation-reduction potentials. See 



Oxidation-reduction potentials. 

 protein specificity and enzymic 

 activity, 338, 339 

 Hemorubin, 539 

 Hemosiderin, 507, 568, 614, 615 

 Hemoverdin, 471, 478 

 Hepatocuprein, 619 

 Hepta-coordination, 180, 181, 220 

 Histidine 



in cytochrome c, 232, 352, 357 (table) 

 hemochromes, 232 



imidazole and protein-iron linkage, 

 232-238 

 objections to imidazole hypothesis, 

 238 

 in peroxidase, 424 (table), 426, 427 

 in respiratory pigments, 232, 315 

 (table), 316 (table), 317 



