742 



SUBJECT INDEX 



Porphyrins (confd.) 



fluorescence, 76, 88. See also Ery- 

 fhrocyte. 

 pH curves, 77 

 formation in vivo. See Porphyrin 



formation. 

 HCl-number, 68, 69 (table) 

 historical, 47 

 isolation, 85 

 isomerism, side chain, 6, 54 



nuclear, 83 

 in liver, 581, 630. See also Proto- 

 porphyrin. 

 metabolism, 577 ff. See also Porphyrin 

 formation. 

 in animals, 584 

 in man, 578 ff. 

 metal complexes. See Porphyrin metal 



complexes. 

 in nervous system, 581 

 nomenclature and symbols, 53 

 occurrence, 48, 50 (table) 

 paleontology, 648 

 pK number, 69 

 pharmacology, 601 

 photosensitization, 599 

 protein compounds, 71, 240, 241 

 resonance, 78 ff . 

 separation, 85, 86 (table) 

 in serum, 580 



solubility and acid base character, 59, 68 

 stereochemistry, 80 

 structure, of ring system, 3, 48, 49 ff. 



side chains, 6, 49, 51-3 (tables), 62 

 synthesis, 7, 56 

 toxicity, 600 

 in urine, 47, 583, 586, 588. See also 



Porphyrinuria. 

 Verteilnngazahl, 69 

 Porphyrins c, 204, 350 



from cytochrome c, 350 

 Porphyrin formation in vivo 



by aromatic amines, 590 (table), 596 

 by bacteria, 581, 631 



from hematin compounds, 592 

 and bile pigment formation, 594, 595 

 from hematin and hemoglobin, 597 

 by hemoglobin breakdown, 598 

 in hemoglobin synthesis, 628 

 in hemolytic diseases, 593 

 in lead poisoning, 578, 596. See also 

 Porphyrins (excretion) . 



in liver disease, 583, 590 (table), 591 



(table), 594 

 from myohemoglobin, 599 

 from respiratory enzymes, 599, 627 

 synthesis of nucleus, 608, 610, 632 ff. 

 and carbohydrate metabolism, 632, 



637-641 

 decarboxylation of precursor, 636, 



637, 638, 641, 642 

 and hemopoiesis, 643-645 

 nitrogen precursor, 637 

 theory of, 632 ff., 637 ff. 

 in yeast, 632 

 Porphyrin metal complexes, 6, 48, 93, 94 

 (table), 159 ff., 192. See also Hem- 

 atin compounds. 

 absorption spectra and bond type, 162, 



192 

 in bacteria, 631 

 copper, as oxidases, 337 

 and globin, 240 

 magnetochemistry, 21, 22 (table), 24, 



25, 160, 192 

 of Mn, Co, Ni, 192, 193 (table) 

 stereochemistry, 159 

 in urine, 589 

 Porphyrinuria, 589, 590 (table), 591 



(table) 

 Potentiometry, 25 



dissociation constants, 26 

 electrometric titration curves of pro- 

 teins, 27, 28 

 oxidation-reduction potentials, 28 ff. 

 Prodigiosin, 152 

 Propentdyopent, 149, 150, 151 

 Protoporphyrin, 48, 50 (table), 51 (table), 

 53 (table), 60, 69 (table), 70, 72, 74 

 (table), 75 (table), 76 (table) 

 in chloroma, 581, 598, 599 

 and coproporphyrin, 582, 583, 596, 629, 



637, 641 

 in earthworm, 50 (tal)le) 

 in erythrocytes, 579. See also Ery- 

 throcyte. 

 fate of injected, 582, 583 

 formation from hemoglobin, 598 



in putrefying blood, 60 

 as growth factor, 608 

 in Harderian gland, 50 (table), 584 

 isolation from erythrocytes, 86 

 in meat autolysis and putrefaction, 592 

 ooporphyrin, 50 (table), 60, 585 

 in placenta, 585 



