THE PITUITARY BODY 



amputated limb was increased in axolotls if the animals were 

 kept in water containing 0.25 cc. of a pars-neuralis extract per 

 liter. Herrell (1934) studied the regeneration of the tail in 

 tadpoles {R. clamitans) 6-8 months old. Apparently he added 

 a solution of anterior pituitary extract ("Antuitrin G") to the 

 water in which the tadpoles were kept. Tail-regeneration 

 took place at a slower rate if the extract was added before or 

 shortly after the partial amputation; regeneration occurred 

 more rapidly and even extended beyond the normal size if the 

 addition of the extract was postponed to the later "prolifera- 

 tive" or "differentiative" phases of regrowth. The extract 

 also brought about an increased growth of the body and tail 

 of normal tadpoles. 



According to Wulzen (1916), the fission-rate of planarian 

 worms is increased by feeding any part of the pituitary body. 

 In comparisons of the growth-rate of such worms on diets of 

 liver or of different parts of the pars glandularis, she later 

 showed (1930) that growth was most accelerated in worms 

 fed on a diet of liver; however, a diet of pars glandularis, com- 

 posed chiefly of oxyphil and reserve cells, produced more 

 growth-acceleration than did a diet of pars glandularis com- 

 posed of basophil and reserve cells. 



The experiments of Thompson (1929), who fed lettuce 

 which had been dipped in an extract of the pars glandularis to 

 silkworms, cannot be evaluated because the experiments 

 were inadequately controlled and not enough data are given. 

 According to Patterson (1925) flies (probably Sarcophaga 

 sarcena and Calliphora erythrocephald) do not grow or meta- 

 morphose more rapidly if their food is restricted to the pars 

 glandularis or to other parts of the pituitary body undergoing 

 decomposition. 



Both Wulzen (1914) and Pearl (1916) reported that the 

 feeding of the pars glandularis of the ox to fowls caused a re- 

 tardation of growth which was manifested by changes in the 

 weight and in the length of bones. Wulzen also observed that 



[84] 



