THE EFFECTS OF HYPOPHYSECTOMY 



stated that diabetes insipidus was observed in dogs after the 

 destruction of the tuber cinereum irrespective of the presence 

 or absence of the pituitary body; but others have concluded 

 that polyuria does not occur if the tuber cinereum has been 

 destroyed (see p. 74). 



The hormone increasing the dispersion of chromatosomes 

 in chromatophores (melanophores and erythrophores) has 

 been thought to occur in cerebrospinal fluid after hypophy- 

 sectomy (Sato) or to be present in increased concentration as 

 a result of the faradic stimulation of the hypothalamus (ex- 

 periments in cats by Karplus and Peczenik, 1930, 1933). The 

 latter authors also believed that the cerebrospinal fluid con- 

 tained more pressor principle after the stimulation of the 

 hypothalamus. 



79 



