ANATOMY OF THE PITUITARY BODY 



gether at the periphery of the cell. These cells can also be 

 found in large numbers in the pars glandularis of spayed fe- 

 male rats (see Fig. lo). With Addison's general conclusions 

 as to the changes in the basophils of the rat's pituitary after 

 gonadectomy there is a refreshing agreement among most 

 authors (Nukariya, 1925; van Wagenen, 1925; Schenck, 





Fig. 10. — The effect of spaying on the basophil cell of the rat (Ellison and 

 Wolfe, 1934). Photomicrographs. Xi,66o. Nos. 3, 4, Basophils in the pituitary 

 of normal female rats. Nos. 5, 14, 17, 18, Basophils in the pituitary of spayed rats. 

 Nos. 17 and 18 conform to descriptions of "castration-cells." 



1927; Lehmann, 1928; Severinghaus, 1933; and others). 

 Schenck (1929) reported that twenty months after castration 

 no typical castration-cells but intermediate types of basophils 

 could be found. Schultze (1934) believed that the most pro- 

 nounced changes in the pituitary of gonadectomized female 

 rats occurred in those gaining the most weight after oper- 

 ation. Actual counts of the number of different cell types of 

 the pars glandularis of normal, spayed, and castrated rats 



[25] 



