THE PITUITARY BODY 



can produce increased secretion of oestrin by the ovary with- 

 out associated morphological changes. Fels (1930) excised 

 the ovaries of immature rats about 30 hours after the first in- 

 jection of prolan; although the ovaries histologically ap- 

 peared unchanged, oestrus was observed later. Transplanted 



Fig. 34. — The effect of prolan on the uterus and ovaries of the immature rat. 

 The dose was distributed over 4 days. Specimens from Httermate rats 26 days old 

 at death. Body-weights: control (middle), 54 g.; bottom and top receiving same 

 dose of prolan, 55 and 51 g. Scale in cm. See Figure 35. 



ovaries also respond to the injection of prolan. Goodman 

 (1934) transplanted the ovaries of immature rats into the 

 anterior chamber of the eyes of adult male and female rats. 

 In both, corpus luteum formation occurred following the in- 

 jection of prolan. Without prolan administration there oc- 



[188] 



