GONADOTROPIC SUBSTANCES 



curred complete cyclic changes including corpus luteum de- 

 velopment in the ovaries transplanted into the eyes of adult 



Fig. 35. — Photomicrographs of uteri and ovaries of specimens of Figure 34, 

 X13.5, arranged in same order: control, middle; injected with same dose of prolan, 

 bottom and top. Predominant changes in bottom specimens: oestrin effect on uter- 

 us; follicle growth with some corpus luteum formation and some lutein-cell forma- 

 tion within ripening follicles in ovary. Predominant changes in top specimens: 

 condition of uterus corresponds more to adult dioestrous (corpus luteum) stage; 

 corpus luteum formation with hemorrhage into cavity of one corpus luteum and 

 probably some follicle-ripening in ovary. 



females, but only follicular maturation in those transplanted 

 into the eyes of adult males. In the past, some have ques- 



[189] 



