CHAPTER VIII 



THE INTERRELATIONSHIPS BETWEEN THE PARS 

 GLANDULARIS AND THE ADRENALS, PAN- 

 CREAS, PARATHYROIDS, AND THYMUS; EX- 

 PERIMENTAL EVIDENCE THAT THE METABO- 

 LISM OF FOODSTUFFS DEPENDS PARTLY UPON 

 INTERNAL SECRETIONS OF THE PARS GLANDU- 

 LARIS^ 



TO COMPLETE the discussion of the physiology of 

 the pars glandularis, interrelationships between the 

 anterior lobe and other glands of internal secretion 

 will be considered in this chapter. The experimental evidence 

 for and against the belief that the pars glandularis affects the 

 metabolism of various foodstuffs will also be reviewed. 



THE INTERRELATIONSHIP BETWEEN THE ANTERIOR 



PITUITARY AND THE PARATHYROID GLANDS, 



THE THYMUS, AND THE ADRENAL GLANDS 



The interrelationship between the anterior pituitary and the 

 parathyroid glands.- — The effect of hypophysectomy on the 

 parathyroid glands has been studied by only a few investi- 

 gators. As a result of the removal of the hypophysis (pars 

 buccalis) from tadpoles, the epithelial bodies, which are 

 homologous with the mammalian parathyroid glands, under- 

 go atrophy (Smith). ^ Dogs were used in the experiments of 

 Houssay and Sammartino (1933). They concluded that atro- 



' Other references to nearly all the topics discussed in this chapter will be found 

 in the Index. 



^ Charles (1931) found that there was a reduction in the concentration of calcium 

 in the serum of female toads {Xenopus laevis) amounting to 20-37 P^^" cent after 

 the removal of the anterior lobe or of both the anterior and the posterior lobes of 

 the pituitary. 



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