Xll 



CONTENTS 



CHAPTER IV. 

 THE SEAT OF PRODUCTION OF THE 

 SECRETION OF THE TESTICLE . 



INTERNAL 



A. Mammals ....... 



I. The Interstitial Cells of the Testicle 



The Ligature of the Vas Deferens 



The Retained Testicle .... 



The Engrafted Testicle .... 



The Influence of X-Rays on the Testicle 



The Relation between the Quantity of Interstitial 



Tissue and the Hormonic Effect 



{a) Is there a compensatory hypertrophy in the 

 Testicle? ..... 



{b) The Law of "All or Nothing " 



7. On Cyclic Changes in the Development of the 



Interstitial Tissue .... 



8. The Phases of Puberty in the Male . 



9. The "Follicular Theory" of Hormone-Production 



in the Testicle . . . 



10. The Condition of the Interstitial Cells in Intoxica 

 tion and Disease ..... 

 Conclusions ....... 



B. Interstitial Cells in the Testicle of other Species 



1. Invertebrates ...... 



2. Fishes ....... 



3. Amphibians ...... 



4. Birds ....... 



Bibliography ....... 



CHAPTER V. 

 THE SEAT OF PRODUCTION OF THE INTERNAL 

 SECRETION OF THE OVARY 



A. Mammals ....... 



1. The Interstitial Cells of the Ovary 



2. The Origin of the Interstitial Cells of the Ovary 



3. The Influence of X-Rays on the Ovary 



4. Transplantation of the Ovary 



5. The Condition of the Ovary in Partial Castration 



6. The Internal Secretion of the Corpus Luteum 



{a) Histogenesis of the Corpus Luteum 



(6) The Functional Relationship between the 



Corpus Luteum and the Interstitial Tissue 

 {c) Objections to the Theory of the Internal Secre 



tion of the Corpus Luteum 



7. The Phases of Puberty in the Female 

 Conclusions ....... 



B. Other Vertebrates . . . , 



Bibliography ....... 



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