RESULTS OF CASTRATION 



23 



castration is performed on a younger animal with horny styles 

 about 2 mm. long, the latter diminish as far as the bottom of 

 the blind sac, and no horny styles can be seen with the 

 naked eye or magnifying glass {Fig. 10, Cb). In how striking 

 a manner the result varies according to the age at which 

 castration was performed, is also shown by our observations 

 on the penis in general (Figs. 10 and 11) and on the vesiculae 

 seminales {Figs. 12, 13, 14). A detailed histological exami- 

 nation of the changes the vesiculae seminales undergo in the 

 guinea pig after castration was made by Gley and Pezard 

 (1921). The epithelium, normally cylindrical, becomes cubical. 



Fig. 13. — Seminal vesicles oj 

 a guinea pig 21 months old 

 castrated at the age of 2 weeks 

 (Prot. Nr. 23). Nat. size. 



Fig. 14. — Sei)iuictl cc sides of guinea 

 pig castrated at the age of 4^ 

 months, drawn 11 months later 

 (Prot. Nr. 27). 



and loses its granulation. By this fact the changes in the 

 secretory activity of the vesiculae seminales after castration 

 can be explained. Similar observations were made by N. F. 

 Fisher (1923) in the rat. As was stated by Gley and Pezard 

 and by myself, the secretion of the vesiculae seminales, which 

 normally coagulates under the influence of the prostatic juice, 

 does not coagulate after castration. 



A characteristic feature in the castrated guinea pig is the 

 accumulation of preputial secretion on the penis {Fig. 11). 



The penis remains undeveloped or infantile after ptepuberal 

 castration also in the rabbit, as was stated by Richon and 

 Jeandelize (1903). They castrated rabbits of one to two 

 months old, and observed them during one year. The differ- 

 ence between the penis of a normal adult rabbit and that of a 

 prepuberally castrated animal of the same age is extraordinarily 

 striking {Fig. 15, B and C). The distal part of the corpora 

 cavernosa penis, designated as a glans penis, is absent after 



