236 INTERNAL SECRETIONS 



the graft consisted almost entirely of lutein cells. They 

 stated also (1907) that in the rat the transplanted ovary can 

 undergo cychcal changes hke the normal ovary. They found 

 in the graft at the commencement of the breeding season large 

 follicles, afterwards also corpora lutea. Evidently ovulation 

 can take place in the transplanted ovary. According to all 

 authors who have made histological observations on the ovarian 

 graft, the difference between a normal ovary and an ovarian 



i 



Fig. 107. — Section through ovary engrafted six months previously into 

 a castrated male, x 25. Increased follicular atresia. — From 

 Steinach. 



graft seems to be merely that there is an accelerated atresia 

 of those follicles which have already attained a certain 

 size at the time when transplantation was performed. There 

 is possibly also an accelerated atresia afterwards. By this a 

 predominance or an hypertrophy of interstitial tissue consisting 

 of epithelioid, or lutein cells, is caused. 



Several authors have made histological observations also on 

 the condition of the ovarian graft in a normal or castrated 

 male. W. Schultz (1900) was the first to show that an ovarian 

 graft can "take" in a male organism, even when the latter has 



