INTERNAL SECRETION OF OVARY 229 



" Case 2" and "Case 3 " could end both with atrophy of the inter- 

 stitial tissue and re-estabhshment of the normal condition of 

 the ovary. Chnical observations make it probable that by 



:.»iS»iS*i!it"»'& 



„.ij 



^m 



r*. 



-t^t^n-S-^iV-tW**^- 



• %. -T^ 



B 



Fig. 105. — Influence of X-rays on sex characters in virginal 

 female guinea pig. — From Steinach and Holzknecht. 

 Normal virginal guinea pig, 4I months old. 



A. Uterus (before bifurcation), x 9. 



B. Ovary, x 18. Follicles at different stages of 



development. 



therapeutical irradiation some kind of a transition between 

 "Case 2" and "Case 3" is generally brought about ; there is an 

 injury of the folhcles, but evidently not so great and not 



permanent, as in "Case 2." Paul Werner (1918), who has 



