244 



INTERNAL SECRETIONS 



by the fact that a relatively larger number of ova enters upon 

 follicular development. 



In our experiments with partial castration of rabbits we 

 were able to demonstrate that this suggestion is justified. 

 In fragments which represented originally a quarter and a 

 half of an ovary (the second ovary having been removed), 

 and which attained the volume of about a normal ovary, we 

 found that the number of young ova was very reduced (Fig. no). 





Fig. 



iio.^ — Decrease of number of oocytes in ovarian fragment, x 200. 

 A. Section through ovary of rabbit 7 months old (Prot. Nr. 136). 



Prepar. of Wagner; photo of KulL 



In another case which we described in the foregoing 

 section, the number of young ova in the hypertrophied frag- 

 ments was extraordinarily small, representing only about two 

 or four per cent, of the normal On the contrary, the number of 

 ripening follicles and the quantity of interstitial tissue were 

 as large as in a normal ovary. Evidently the majority of 

 young ova had been used up in follicular development. 



In view of all these observations it seems clear that hyper- 

 trophy of ovarian tissue implies that a relatively larger 



