438 INTERNAL SECRETIONS 



precocity as far as it can be based on cUnical data is still very 

 incomplete. I find no real basis for a proper explanation of the 

 condition, though various experiments with administration of 

 thyroid or hypophysis and with removal of the pineal gland 

 perhaps give some indication of an hormonic basis for sexual 

 precocity. The paper of Krabhe (1923) may be referred to here. 

 Steinach (19 16) claims that sexual precocity may be observed 

 in guinea pigs and rats. According to him the precociously 

 developed male rat can be recognised by the occurrence of a 

 hairiness at a time when the other animals of the litter are still 

 bare. The precocious animal is said to grow quicker than the 

 normal one, and the penis, prostate and seminal vesicles to 

 develop earlier ; erection and sexual activity may be observed. 

 According to Steinach in such animals there is also a normal 

 development of the seminal tubules, but an hypertrophy of the 

 interstitial cells. But these observations, in my judgment, 

 are not very convincing. 



BIBLIOGRAPHY TO CHAPTER X. 



Aschner. 1918. Die Blutdrusenerkrankungen des Weibes. Wies- 

 baden. 



AsKANAZY. 1921 ( ?). Die Zirbel mid ilire Tumoren in ihrem funk- 

 tioneUen Einfluss. Frankf. Zeitschr. /. Pathol., 24, p. 68. 



Baar. 1920. Makrogenitosomia praecox — Zirbel tumor. Zeitschr. /, 

 Kinderheilkunde, 27, p. 143. 



Bell. 1920. The Sex-Complex. London. 



Berblinger. 1921. tJber die Zwischenzellen des Hodens. Verhandl. 

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BiEDL. 1913. Inner e Sekretion, Vol. II., 2nd edition. Berlin -Wien 

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BoEHM. 1919. Zirbeldriisenteratom und genitale Friihreife. Med. 

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H ALB AN. 1921. Keimdriise und Geschlechtsentwicklung. Archiv 

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HiRSCHFELD. 1916. Uber Geschlechtsdriisenausfall. Neurolog. Zen- 

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1917. Sexualpathologie, Vol. I. Bonn. 



