i6o8 



HANDBOOK OF PHYSIOLOGY 



CIRCULATION II 



AMNIOTIC 



fig. 22. Identical pressures in amniotic 

 fluid and intervillous space of placenta in the 

 monkey with the uterus contracted or relaxed. 

 [Permission of Ramsey et at. (,i 88.] 



5 10 



C-772 138 DAYS 



AMNIOTIC 

 Average tonus 16 



Average amplitude 18 8 



I. VS. 

 Average tonus 4 I 



Average omplitude:20 8 



fig. 23. Failure of India ink to reach a sinus 

 structure at margin of monkey placenta. [Per- 

 mission of Ramsey (185).] 



fig. 24. Injected lymphatics in uterus of a 

 nearly mature rhesus monkey. Note paucity in 

 superficial endometrium. (From Wislocki & 

 Dempsey. Anal. Record 75: 341, 1939.) 



M vometrium' 



uterine relaxation, reactive hyperemia set in. After 

 labor, there was a precipitous fall in uterine blood 

 flow which declined gradually with subsequent uterine 

 involution. 



The action of oxytocic, vasopressor, and vaso- 

 depressor drugs on postpartum uterine blood flow- 

 was studied by the same method [Assali et al. (11)]. 

 Both natural and synthetic oxytocics in large doses 



cause an initial rise, followed by a marked decline in 

 uterine artery blood flow. Epinephrine produces no 

 significant change in uterine blood flow, although 

 norepinephrine increases the diastolic pressure and 

 mean blood flow. Apresoline (a sympatholytic agent) 

 increases blood flow substantially. 



In a study of uterine blood flow and uterine metabo- 

 lism in women, Assali et al. (12) report that blood 



