719-4 
determined. The last-named substance is spoken of by some observers as being 
resinous, others as resinoid, and again as crystallizable. I judge it to have been 
in all the Eupatorine of Latin, either mixed with some part of the other constitu- 
ents, or more or less pure. 
PHYSIOLOGICAL ACTION.—The symptoms shown by those who have par- 
taken of large doses of an infusion of the tops and leaves, show that this drug 
causes at first an irritation of the vaso-motor system, followed by a relaxed condition 
of the capillaries, and an increase of the heart’s action, again followed by severe 
congestion and higher temperature. The symptoms are: Faintness, with loss of 
consciousness, ending in lethargic sleep; pain, soreness, and throbbing in head; 
soreness of eyeballs, with sharp pains and photophobia; buzzing in the ears; 
catarrhal influenza; face red or sallow, and sickly in appearance; tongue white . 
cottony coated ; thirst especially preceding the stage of chill; vomiting, especially 
as the chill passes off; violent colic pains in the upper abdomen; urine dark- 
colored and scanty, with frequent micturition; oppression of the chest with difficult 
breathing ; stiffness, soreness and deep aching in the limbs, the long bones espe- 
cially, feel as if pounded or broken ; sleepiness, with yawning and stretching, from 
which the patient awakes with a severe headache; skin bathed in copious sweat. 
The soreness and deep pains of Eupatorium are most general, and the skin feels 
numb and as if it would cleave from the bones. 
The adaptability of this drug to various forms of disease of paludal origin ~ 
can readily be understood. 
DESCRIPTION OF PLATE 79. 
1. Summit of stem, from Greenville, N. J., July 26th, 1879. 
2. Flower-head. 
3- Floweret. 
4. Anther. 
5- Fruit. 
(2-4 enlarged.) 
