180 EXPERIMENT STATION EECOED. 



Tuberculosis and the tuberculin reaction, Romer and Joseph (Beitr. 

 Klinik. Tuberkulose, 17 (1910), No. 3, pP- Jf27-460, jHs. 8; abs. in Ztschr. Im- 

 munitatsf. u. Expt. Then, II, Ref., 3 {1910), No. 8, p. 858).— For the bovine, 

 the intra- and subcutaneous tuberculin tests are almost absolutely reliable. The 

 intracutaneous test is deemed the only reliable reaction for hogs and guinea 

 pigs. The author recommends the puncture and the intracutaneous reactions 

 for man. 



In regard to the thermal tuberculin reaction in bovines, E. Hauptmann 

 (TierUrztl. ZentU., 33 {1910), Nos. 9, pp. 133-139; 10, pp. 150-158; 11, pp. 

 170-175; 12, pp. 181-186; ahs. in Berlin: Tierdrztl. Wchnschr., 27 {1911), No. 

 10, p. 181). — This is a study of the effect of repeated injections of tuberculin 

 upon the diagnostic value of the tuberculin reaction. The author points out, 

 among other things, that the rule set up by Koch in regard to the interpreta- 

 tion of the tuberculin reaction is of value for bovines only when long intervals 

 elapse between the injections. 



The effect of the injection of the various tuberculins and of tubercle 

 endotoxin on the opsonizing action of the serum of healthy rabbits, R. T. 

 Hewlett {Proc. Roy. Soc. Med. [London], 3 {1910), Nos. 6, pp. 165-168; abs. 

 in Internat. Centbl. Gesam. Tuberkulose Forsch., 5 {1910), No. 1, p. 25). — 

 This work shows that old tuberculin had practically no effect on the opsonins in 

 healthy rabbits, while the tubercle endotoxin (prepared by trituration from a 

 culture of human tubercle bacilli, filtration, and standardization) produced a 

 more marked stimulus on the opsonizing activity than either tuberculin I. K. 

 or tubercle bacillary emulsion. The author suggests that this may be a more 

 active therapeutic agent than either old tuberculin, tuberculin T. R., or bacil- 

 lary emulsion. 



In regard to tuberculins which have the poisonous principle removed, 

 A. Wolff-Eisner {Berlin. Klin. Wehnsehr., J,7 {1910), Nos. //7, pp. 21.'f7-2150; 

 48, pp. 2200-2202; abs. in Ztsohr. Immunilutsf. u. Expt. Then, II, Ref., 3 

 (1910), No. 10, p. 9-'{8). — This is a critical discussion and report of some in- 

 vestigations in regard to 2 new tuberculin preparations (Hochst's new tubercu- 

 lin, and Endotin). Both gave results which were comparable to the usual 

 tuberculin reactions. 



The detection of tuberculosis with Bovotuberculol, Kranich (Berlin. 

 Tierdrztl. Wehnsehr., 27 (1911), No. 19, pp. 3.'fl-3.'t-'f). — If the specifications are 

 adhered to, the ophthulmo-reaction with Bovotuberculol is a more convenient 

 and reliable method than the subcutaneous injection of tuberculin. 



The technique of determining the opsonic index, H. Reiter (Deut. Med. 

 Wchnschr., 36 (1910), No. 52, pp. 2Ji26-2428; abs. in Ztschr. Immimitdtsf. u. 

 Expt. Ther., II, Ref., 3 (1910), No. 11, p. 995). — This is an exact and detailed 

 discussion of the methods and principles involved for determining the opsonic 

 index. 



Practical results with the intracutaneous tuberculin reaction with hogs 

 and bovines, G. Martin (Beitr. Klinik Tuberkulose, 16 (1910), No. 1, pp. 

 37-5Jt; abs. in Internat. Centbl. Gesam. Tuberkulose Forsch., 5 (1911). No. 5, 

 p. 24O). — The author recommends this reaction for general veterinary practice. 



In regard to the clinical utility and the nature of the complement fixa- 

 tion reaction according to Marmorek, D. Klinkert (Ztschr. Expt. Path. u. 

 Ther., 8 (1910), No. 2, pp. 451-.i6Ji). — Marmorek modified the complement fixa- 

 tion method in so far that with it it was possible to diagnose tuberculosis with 

 the urine or blood from a tuberculous subject. The author investigated the 

 value of the test with GOO subjects (306 serum and 294 urine), and from the 

 work he concludes that Marmoreli's reactioii is a good scientifig BJethod for 



