VETERINARY MEDICINE. 181 



the diagnosis of tuberculosis, but tliat tlie results obtained witli it are uot 

 specific enough. 



The meiostagmin reaction in experimental tuberculosis, A. Gasharrini 

 {Munchen. Med. Wchnschr., 51 {1910), No. 32, p. 1688).— The meiostagmLa 

 reaction according to the author can be employed for the differentiation of 

 tuberculosis caused by the bovine or human type of bacillus. 



Experimental studies in tuberculosis, Romee and Joseph (Beitr. Klinik. 

 Tuberkulose, 17 (1910), No. 3, pp. 2S1-2S5, fig. 1; abs. in Ztschr. ImmunitUtsf. 

 u. Expt. Ther., II, Ref., 3 {1910), No. 8, pp. 856, 857).— A. reinfection with the 

 tubercle bacillus could not be produced by cutaneously injecting 0.000,001 mg. 

 of bacillus emulsion if the animals in question were injected subcutaneously 

 from 2 to 14 months previous to the second injection and were allowed to 

 acquire a slowly progressing tuberculosis. Intracutaneous doses less than 

 0.000,001 mg. were also ineffective. 



For refuting some of Joest's findings (E. S. R., 23, p. 687) the authors extir- 

 pated a tuberculous lymphatic gland from a guinea pig, made it into an 

 emulsion with physiological salt solution, and injected it iutracutaneously into 

 the same guinea pig. This animal could not be infected the second time. A 

 control pig inoculated at the same time succumbed to the disease. 



Other tests continued along the same lines showed somewhat similar 

 results. 



Prophylactic vaccination against tuberculosis, Maeffskij {Arch. Vet. 

 Nauk. [St. Petersh.], J,0 {1910), No. 4, pp. Jtll-Jf23; abs. in Ztschr. Immuni- 

 tdtsf. u. Expt. Ther., II, Ref., 3 {1910), No. 9, pp. 906, 907).— The author 

 points out that calves do not, as is generally assumed, act indifferently toward 

 the Koch-Schiitz Tauruman vaccine; instead, 15.36 per cent of the animals 

 became sick after the vaccination. Tauruman vaccination for calves affected 

 with tuberuclosis has a tendency to hasten the course of the disease, and not 

 seldom (3.6 per cent of the cases) does it cause death. The duration of 

 immunity with this vaccine is limited, and usually lasts only one year. 



Combating tuberculosis in hogs, A. Eber {Ztschr. Fleisch u. Milchhyg., 20 

 {1910), No. 10, pp. 321-326; abs. in Internat. Centbl. Gesani. Tuberkulose 

 Forsch., 5 {1911), No. 5, p. 251). — A general discussion in regard to the occur- 

 rence of this disease in hogs, and the relation which the feeding of skim milk 

 has to it. 



The author does not believe that centrifuging the milk will make it more 

 sanitary for this purpose. 



Contribution in regard to the nature of tuberculosis-immunity-antibody 

 studies, RoMER and Joseph (Beitr. Klinik Tuberkulose, 17 (1910), No. 3, pp. 

 365-382; abs. in Ztschr. Immunitatsf. u. Expt. Ther., II, Ref., 3 {1910), No. 

 8, pp. 85-'i, 855). — For these tests the author utilized sheep which had been 

 repeatedly tested in regard to their active immunity. 



From the results it may be noted that immunity against tuberculosis may 

 exist in the absence of agglutinins in the blood; complement deviating sub- 

 stances were not present in every case, and bacteriotropins were not looked 

 for. Anticutins were looked for in the serum of immune guinea pigs by mixing 

 tuberculin with the serum of immune guinea pigs and injecting this iutra- 

 cutaneously into guinea pigs. The results were negative. 



Bactericidal and anti-infectious substances were not found in sheeps' 

 blood ; the serum of immune sheep never conferred immunity upon normal 

 guinea pigs. 



Studies in immunity to tuberculosis. — Hypersensitiveness to tuberculo- 

 protein and its relation to some tuberculosis problems, A. K. Krause {Jour. 

 Med. Research, 24 {1911), No. 2, pp. 361-409, tables 3).—" This inquiry resolved 



