284 EXPERIMENT STATION EECORD. 



The conjunctival test (ophthalmo i-eaction) under certain conditions is of 

 value for forensic worlc, and a subcutaneous injection of tuberculin will not 

 influence the test. The ophthalmo reaction only appears when tuberculosis is 

 present and is considered cheaper, talces less time, and is more reliable than 

 the subcutaneous test. A previous conjunctival test will not influence the 

 results of the superseding ophthalmo test. 



In regard to Calmette's cobra venom activation method for diagnosing 

 tuberculosis, P. Bermbach (Ztschr. Tuherkulose, 17 (1911), No. .}, pj). 33Jf- 

 339). — According to Calmette, certain sera after inactivation can stimulate 

 cob^a venom to hemolyze washed red blood corpuscles which had been pre- 

 viously freed from serum. This venom activating substance is bound to 

 lecithin. 



The sera from 19 cases of tuberculosis of man were examined in regard to 

 hemolysis — only 4 showed complete hemolysis. Among the 15 negative cases 

 5 were positively tuberculous in character, 7 nontuberculous, and 3 doubtful 

 cases. 



The ether-antiformin method for tubercle bacilli, Koslow (Berlin. Klin. 

 Wchnsch7:, J,! (1910), No. 25, pp. 1181, 1182; abs. in Internat. Centbl. Gesam. 

 Tmherkalose Forsch., It (1910), No. 10, p. 527). — This is a combination of the 

 ether and anitformin method, and has the advantage of being rapid and not 

 requiring the use of the centrifuge. 



Immunizing against tuberculosis, von Baumgarten, Dibbelt, and Dold 

 (Arb. Path. Anat. u. Bakt., Path. Anat. Inst. Tilbingen, 7 (1910), p. 397; abs. 

 in Centbl. Bakt. [etc.], 1. Abt., Ref., ^P (1911), No. 15-16, pp. 1,92, Jf93).— In 

 previous work the authors vaccinated animals with the human type of bacillus 

 and were able in this way to produce an immunity which lasted over a period 

 of several 5'ears. 



The experiments here reported were conducted with 10 calves with a view of 

 determining the minimal dose of the vaccine. The results show that 20 mg. 

 of vaccine was sufHcient for all practical purposes to produce a high degree 

 of immunity, and 10 mg. in some cases was just as efficient. 



The distribution and longevity of the life of the tubercle bacillus was also 

 observed with 10 adult bovines. In these tests each animal was given from 

 2 to 5 gm. of the vaccine subcutaneously, and {ill animals were slaughtered 

 after a period of from Si to 4 months. Pieces of the various organs, glands, 

 and muscles of the animals were injected into guinea pigs with the result that 

 only 2 of them died, and these where the pieces of the breast glands on the 

 side in which the injection was made were given. They contained tubercle 

 bacilli. 



Results with endotin (tuberculinum purum), B. H. Vos (Ztschr. Tuberku- 

 lose, 17 (1911), No. ^, pp. 3// 0-34 6). —In the years 1909-10 36 cases of tuber- 

 culosis in man were treated with this preparation, which is said not to produce 

 the undesirable symptoms which result from the injection of old tuberculin. 

 None of the advantages claimed for the preparation over old tuberculin could 

 be noted. 



Foot-and-mouth disease 100 years ago, H. Kohl. (Berlin. Tierdrztl. 

 Wchnschr., 27 (1911), No. 30, pp. 538, 539). — A historical discussion in regard 

 to the views of veterinarians with reference to this disease 100 years ago. 



An unusual complication of mastitis necrotica, R. Reinhardt and O. 

 HoFHERR (Berlin. Tierarztl. Wchnschr., 27 (1911), No. 30, pp. 533-536, figs. 

 Jj). — An unusual case of mastitis in a cow is described which was complicated 

 by the presence of a croupous diphtheritic inflammation of the mucous mem- 



