184 EXPERIMENT STATION EECORD. 



UciilDnini (if mail ami dou's. Ihc dchiils of whirh have been proviously published 

 in 1* works. 



The cutaneous and ophthalmic reactions in glanders, Diictkich (Ai'ch. Wiss. 

 II. Pmlct. Ticrhrilk., 3.', (J908), No. 3, pp. 2J,()-,io1 ; ahs. in Jour. Compar. Path, 

 and Thcr., 22 ( /.90.9), No. 3, pp. 257, 258). — In his experiments, the author found 

 that the cutaneous and ophthalmic reactions with mallein gave no positive re- 

 sults in 10 glandered guinea pigs, tliough the results were also negative in the 

 case of 6 healthy ones. Six of 13 glandered horses gave a positive ophthalmic 

 reaction but 2 of the gave reactions of the second degree only. No horse gave 

 a positive cutaneous reaction and a healthy horse gave negative results to both 

 tests. The cutaneous and ophthalmic reactions are therefore deemed so unre- 

 liable in glanders of the horse and guinea pig as to possess no practical value 

 for the purpose of diagnosis. 



Biochemical and therapeutical studies on trypanosomiasis, A. liREiNL and 

 M. NiKRENSTEiN {Ami. Tvop. Med. and Par., 3 (1909), No. 3, pp. 395-/f20).— This 

 is a detailed report of observations on experimental trypanosomiasis, the treat- 

 ment of infections with different pathogenic trypanosomes, and the mechanism 

 of the tlierapeutical action of various trypanocidal compounds. 



Comparative studies of the tubercle bacillus of man and of the domestic 

 animals, W. Zwick (Ztschr. Infektionskranlc. u. Hyg. Haiisticre, Jf {1908), Nos. 

 3-J,, pp. 161-200, pi. 1, figs. 2; 5-6, pp. 321-373; ahs. in Bui. Inst. Pasteur, 7 

 {1909), No. 9, p. 398). — Comparative studies of the tubercle bacillus are here 

 reported in detail. A bibliography of 102 titles is appended. 



Some properties of tubercle bacilli of bovine origin cultivated on glycer- 

 inated beef bile, A. Calmette and C. Guerin {Compt. Rend. Acad. 8ci. [Paris], 

 l.'i9 (W09), No. 18, pp. 716-718). — Experiments have shown that when guinea 

 pigs are inoculated with bacilli cultivated in this way a much greater virulence 

 is developed, although this becomes steadily diminished by successive cultures. 

 Further experiments, on horses and heifers, have shown that with the former 

 the virulence is not only increased but remains so, while with the latter thei*e is 

 the decreasing virulence observed in the guinea pig. 



Bacteriolysis of tubercle bacilli, G. Deycke and H. Much {Miinchen. Med. 

 Wchnschr., 56 {1909), No. 39, pp. 1985-1987; ahs. in Jour. Roy. Inst. Pub. 

 Health, 17 {1909), No. 11, p. 687). — ^Although previous attempts by many work- 

 ers to find a method of dissolving tubercle bacilli in order to obtain those sub- 

 stances that could stimulate the production of effective specific antibodies, had 

 been without a%ail, the authors report success with lecithin, choliu, and neurin, 

 the last-named proving particularly effective. When to 2 cc. of a 25 per cent 

 solution of neurin 0.5 cc. of a thick emulsion of tubercle bacilli was added, a 

 minute after the addition was made a clearing up of the mixture was observed 

 while the control mixture made with normal salt solution or distilled water re- 

 mained thick and turbid. It w'as possible to follow out, under the microscope, 

 the stages of the dissolution of the tubercle bacilli. 



Tuberculosis and its detection {Iowa Sta. Bui. 107, pp. 361-390, fig. 1, charts 

 6). — In part 1 (pp. 3G4-8S2), C. H. Stange briefly considers the methods com- 

 monly used in the detection of bovine tuberculosis. He reports in detail tuber- 

 culin tests and subsequent post mortems made of the college herd, the tempera- 

 ture charts of reacting animals being given. 



In part 2 (pp. 383-387), W. J. Kennedy and W. Dinsmore report experiments 

 upon the transmission of tuberculosis from cattle to hogs. It was found that 

 22 of 28 healthy pigs, kept in a pasture for about 3 months to clean up after 

 a carload of cows affected with tuberculosis, had unmistakable lesions of the 

 disease w^hen slaughtered a short time after removal. Of the 22 tuberculous 

 bogs, the liver was affected in 9 cases, the mesenteric glands in 6, and each other 



