486 EXPERIMENT STATION nKCORl). 



Marine- Hospital Service over similar i)r(Mliicts used in liuman medicine. The 

 reqnest for sudi suiiorvlsion should have the indorsement of the veterinarians 

 and live-stock interests of this country." 



Cocaine and adrenalin as local anesthetics, Dupuis and Van Dkn EhX'KHOUT 

 {Ami. Med. If/.. r,S l!)()!)), \o. II. i,/). lil.'y-U.il : (ihs. in \<l. lice.. 22 (UK)!)), No. 

 1117, pp. 876, 377; Jour. Compnr. Path, and Thrr., 22 (1900), No. J,, pp. 358- 

 360). — The authors highly recommend the comhination of adrenalin with cocaine 

 or similar agents to induce local anesthesia in the horse. A solution consisting 

 of hydrochlorate of cocaine, 0.2r) to 0.30 gm., hydrochlorate of adrenalin (1 in 

 1,000) ^^ drops, and distilled water, 10 gm., suggested by the iiuthors. is said 

 to be useful in diagnosing lameness in the htwer j)<)rtions of the limb. Though 

 stovaine and alypine are i)erfe<'tly efficient substitutes for cocaine the authors 

 do not sec that they are in any way preferable ti) it. 



A contribution to our knowledge of the physiological action of tutin, 

 F. FiTCHETT (Trans. New Zeal. Inst., JfJ (1908), pp. 286-366). — Investigations 

 made on the action of the pure principle tutin (CnHaoO;) confirmed the results 

 of previous observers that it is in itself sufficient to account for the main bulk, 

 if not the whole, of the symptoms of poisoning by the tutu plant. 



" The tutu plant belongs to the natural order (V)riariea\ a small order of very 

 doubtful relationship possessing but a single genus, Coriaria. The gentis in- 

 cludes some 8 or 10 species, and has a rather remarkable distribution, species 

 being met with in south p]urope. South America, China, Japan, north Africa, 

 India (Himalayas), and New Zealand." These plants (Comu-ia ruscifoJia and 

 C thyrnifolia) have been the source of a great loss of sheep and cattle in New 

 Zealand. The American species, C. thyrnifolia, and the New Zealand species 

 are said to be identical. All parts of the plants are poisonous, but their young 

 shoots are more toxic than the leaves and fruit. Experiments upon the action 

 of tutin on mammals, birds, reptiles, amphibia, insects, etc., are reported. 



New trypanosomes, C. Chagas (Arch. Schiffs u. Tropen fli/g., 13 (1909), 

 No. 1, pp. 120-122; abs. in Sleeping Sickness Bur. [Londdn], liiil. 7, pp. 250, 

 251). — Two new trypanosomes ( Trypanosoma minasense and T. cruzi) are de- 

 scribed. The former was found in a marmoset (Hapale peniciUata), while the 

 latter was found regularly in the intestine of a bug (Conorrhiniis sp. ). Try- 

 panosomes were found in a marmoset 20 to 30 days after specimens of this bug 

 had been placed upon it. The trypanosome was not found in other monkeys 

 and the author believes that the marmoset is not the usual host. The dog, 

 guinea pigs, and rabbit were experimentally infected. 



A new species of Trypanosoma in man, C. Chagas (Bui. »S'oc. Path. Exot., 

 2 (1909), No. 6, pp. ,iO>,~.U)l; ahs. in Shrpinp i<ickncss Bur. \ London], Bui. 8, p. 

 300). — In continuation of the above work, the author has been unable to de- 

 termine the species of Conorrhinus \yhich transmits Trypanosoma cruzi. Its 

 bite is said to be very painful. It feeds on the domestic animals as well as 

 man and the author has several times found T. cruzi in them. The disease in 

 man is called Opilacao and has hitherto been regarded as ankylostomiasis. 

 Children, who were attacked by the disease which the author believes is due -to 

 this trypanosome. have their develojinient arrested. 



Trypanosomiasis of mammals in French Congo, J. K^randel (Bui. Sac. 

 Path. Exot., 1 (1908), No. 8, pp. 515-519; abs. in Jour. Trop. Med. and Hyg. 

 [London], 12 (1909), No. 10, p. 151/). — In the regions visited by the author 

 trypanosomiases are the principal causes of mortality among horses and cattle. 



The forms most commonly met with are Trypanosoma dim or ph on and T. con- 

 golense, which he has found in horses, and still more frequently in cattle in 

 Higher Sangha, Mid-Loyone, and the middle valley of the Ouhama. T. cazal- 

 bout was found in cattle which had become infected iu the last-named district 



