586 EXPEEIMENT STATION RECORD. 



berds. "According to reports, decided improvements Lave been effected in indi- 

 vidual herds by tlie adoption of isolation and disinfection, while in others very 

 little has been accomplished. Should the fixation of the complement and 

 abortin tests justify in actual practice the hopes raised by their application in 

 the laboratory, they will not only constitute additional means of establishing 

 the diagnosis after the act, but will furnish a method of diagnosing the disease 

 a considerable time before the uterus has ejected its virulent contents, and so 

 give to measures of isolation their full and undoubted value in practice." It 

 is stated that the internal administration of carbolic acid must be regarded 

 as an absurdity which has gained a certain amount of support owing to ob- 

 servations carelessly collated and carelessly interpreted. " So long as a dis- 

 charge continues to come from the genital passages, we thinli that for hygienic 

 and thera])eutic reasons they ought to be cleansed once or twice daily by the 

 inti'avaginal injection of tepid antiseptic solutions, such as a 2 per cent solu- 

 tion of carbolic acid or a 1 in 3,000 solution of corrosive sublimate, but not on 

 the ground that the injections will disinfect the uterus." 



It is shown that the bovine female can be rendered highly resistant to infec- 

 tion with virulent material by the subcutaneous injection of a comparatively 

 large quantity of active liquid culture of the abortion bacillus, the inoculation 

 to be performed about 2 months before the commencement of pregnancy. While 

 " it is not possible to immunize pregnant animals with living cultures, it is 

 possible, however, that a not inconsiderable degree of inmninity of shorter dura- 

 tion may with safety be bestowed on pregnant animals by inoculating them 

 with a lai-go dose of bacilli which have been l^illed at a low temperature." 



On contagious abortion in cattle, S. Stockman {Vet. Rcc, 22 {1909), No. 

 1102, irp. 13Jf-139). — An address presented before the Royal Counties Veterinary 

 Medical Association, held July -30, 1900. 



The Bang method for the repression of tuberculosis in cattle, B. Bang 

 (Pcnn. Dcpt. Agr. liiil. 112, pp. 28). — An account of the operation of the method 

 originated by the author, which was introduced into Denmark in 1892. 



Abscesses in the lungs and lymphatic glands of sheep, W. Jowett {Agr. 

 Jour. C'lpc (loi/d JJopc, 35 {1909), A'o. 6, pp. 733-735). — Caseous lymphadenitis 

 due to the bacillus of Preisz-Xocard is reported to l)e prevalent in Cape Colony. 



Studies of agglutination reactions in hog cholera during the process of 

 serum production, W. Giltner {Michigan Sta. Tech. Bui. 3, pp. 5-21). — In the 

 investigation here reported the author finds that the blood serum of normal 

 hogs may agglutinate Bacillus cholerw suis in dilutions as high as 1 : 125, of 

 virus hogs as high as 1 : 700, of immune pigs as high as 1 : 1,000, and of hyper- 

 immune pigs as high as 1 : 2,000 and possibly higher. 



" Pigs may l)e killed by injection intravenously or by feeding cultures of 

 B. cholercE suis isolated from virus hogs made sick by intramuscular injections 

 of hog-cholera blood. Pigs immunized according to the Turner-Kolle method 

 may withstand intravenous injections of virulent cultures of B. cholerw 



suis. . . . 



" We have demonstrated that the hyperimmunization process of Dorset-Niles 

 results in the production of agglutinins and immune bodies for B. cholerw suis. 

 We know neither the nature of these innnune bodies nor the constancy with 

 which they occur. It is not determined by our experience whether the produc- 

 tion of immune bodies for B. cholerw suis is the only result, that is, the primary 

 result, of the hyperimmunization process or merely a secondary reaction, inci- 

 dental to the primary production of immunizing substances against the filterable 

 virus. Our experiments are valuable in paving the way for a clearer under- 

 standing of the etiology of hog cholera. Until the etiology of hog cholera is 

 determined by unconti'overtible experimental and clinical evidences, the pro- 



