484 EXPERIMENT STATION EECORD. 



spleen and bone marrow of the host. In the formation of nonflagelhite stages, 

 some of the cytoplasm and the flagellum of the trypanosome are disintegrated. 

 The nontlagellate body contains the nuclens and blepharoplast (kinetonuclens) 

 of the trypanosome. Nonflagellate (latent) bodies can be seen to grow and 

 flagellate, turning into trypauosomes, when placed in fresh, warm, uninfected 

 blood. Latent bodies of T. rhodesicnxc, inoculated into a rat. flagellate and 

 produce trji)anosomiasis. The nonflagellate (latent) bodies of ti\vpanosomes 

 (7'. gambicnse and T. rhodesiense) are the postflagellate stages of one genera- 

 tion of trj'panosomes and the preflagellate stages of the succeeding generation 

 of trypanosomes. There is a life cycle of trypauosomes (T. gambicnse and T. 

 rhodesiense) in A'ertebrate hosts, comparable with those of Crithidia and Her- 

 petomonas in the alimentary tracts of various invertebrates. The latent (rela- 

 tively resistant) stages of trypanosomes occurring in vertebrates are separate 

 from, and in addition to, stages of the parasite which may occur in the inverte- 

 brate carrier (for example, Glossina)." 



Results obtained from the inoculation of dogs with the horse sickness 

 virus, P. and E. Kuhn {Ztsclir. Immiinitdtsf. u. Expt. Ther., I, Orig., 8 

 (1911), No. 5-6, pp. 665-739). — The authors find that horse sickness can be 

 transmitted to dogs through ingestion of the virus. They think that the native 

 jackal, a related species of Canis, may be found to be a carrier of the virus. 



Notes on the bovine plasmoses of Southern Rhodesia, L. E. W. Bevan 

 (Rhodesia Agr. Jour., 8 (1910), No. 1, pp. 74-81).— The author concludes that 

 " young cattle bred in Mashonaland. while themselves tolerant or immune, har- 

 bor in their blood at least 2 species of protozoa, namely, Piroplasma bigeminum 

 and Anaplasma marginale. Blood taken from them and inoculated into sus- 

 ceptible animals gives rise to 2 infections. That caused by P. bigeminum occurs 

 first, and that caused by A. marginale follows at a time when the subject is 

 weakened by the bigeminum infection. Great care is necessary in the selection 

 of blood for inoculation purposes. The constitution and breed of the animal 

 supplying the blood, its origin, and the approximate degree of infection to 

 which it has been submitted since birth, must be taken into consideration, but 

 it is possible to find a blood in which the parasites are attenuated or of sufli- 

 ciently low pathogenicity to produce an infection which can be regulated. 



" The process of immunizing can not be conducted on mechanical lines, but 

 each case must be treated ' on its merits.' The individual resistance of the 

 animal to be inoculated bears an important part. When undergoing the process 

 of inoculation the animal must be kept free from ticks; and even when im- 

 munized, a gross infestation by ticks is to be avoided, as the immunity is likely 

 to break down under severe infection. The process of immunizing involves a 

 severe strain on the animal's system, and checks development. Some of the 

 drugs regarded as specifics against P. bigeminum are not specific against allied 

 parasites." 



In regard to differentiating- the tubercle bacilli from various sources with 

 the aid of bile containing nutrient media, P. Meyer ( Uber die Differenzierung 

 der TnberkclbnzUlen vcrsehiedener Herkunft auf gallehaltigen Ndlirboden. 

 Inaiig. Diss., Giesscn, 1910, pp. 38; ahs. in Ztschr. Tuberktilose, 17 (1911), No. 

 2, p. IS-'i). — The bile of the human being, bovine, dog, fowl, pig, and sheep in 

 ordinary media in most instances partially inhibits the growth of the tubercle 

 bacillus from bovine, human, and avian sources. The inhibition varies with the 

 source of the bile, and particularly when the bile of one animal species is em- 

 ployed for cultivating the tubercle bacillus obtained from another animal 

 species. 



In regard to combating bovine tuberculosis, M. Klimmer (Schweiz. Arch. 

 Ticrheilk., 52 (1910), No. 6, pp. 382-406, fig. 2; abs. in Ztschr. Imnwnitatsf. u. 



