VETERINARY MEDICINE. 485 



Expt. Ther., II, Ref., 3 (1910), No. 13, p. 1099).— The author in this article 

 recouimends the use of antiphymatol for vaccinating against tuberculosis. The 

 active principle of this preparation is obtained from human tubercle bacilli 

 which have been prepared by passing them through cold-blooded animals and 

 subjecting them to low temperatures, as a result of which the bacteria lose 

 their infectious characters. The bacteria so prepared, according to the author, 

 do not multiply when introduced into the system. He points out the limitations 

 of this preparation and of its use as a curative agent. 



Antiphymatol (Klimmer) and Klimmer's segreg'ation method, E. Haupt- 

 MANN {TierUrztL Zetitbl., 33 (1910), A'os. 34, pp. 5U-550; 35, pp. 559-56-'i; abs. 

 in Ztschr. Immunitdtsf. u. Expt. Ther., II, Ref., 3 {1910), No. 13, pp. 1095, 

 1096). — These tests extended over a period of 2 years and were made with 125 

 bovines, among which, before segregation. 70 per cent gave a positive (phymatin- 

 hunian) ophthalmic reaction. 



Among the 30 animals which at the outset did not react toward phymatin, 

 and which were vaccinated twice the first year and once the following year 

 with antiphymatol, 5 after from 1^ to 2 years were found to be sound on 

 slaughter, despite the fact that during the interval the animals were kept in 

 a barn containing diseased animals, some having open tuberculosis. The re- 

 maining healthy animals were not affected in the least by the vaccination, with 

 the exception that the yield of milk on the day of the vaccination was decreased 

 an average of 2 liters per head. No hygienic precautions other than the injec- 

 tion were taken with the animals. 



Out of 79 animals which gave a positive ophthalmic reaction, 26, among the 

 number 3 clinical cases and 2 emaciated " coughers,'' were injected 4 times 

 during the first year with antiphymatol in order to determine its curative 

 action. Two of the clinical cases were slaughtered after the second injection 

 and showed widely distributed inflammation of the pleura. The 2 " coughers " 

 which were injected 4 times were found on slaughter to be markedly tuber- 

 culous. A clinical case is still living and is in a good constitutional condition. 

 The other clinical case after slaughter and after a period of 1^ years showed 

 capsulated foci. In 7 clinically sound cases f of a year after the close of the 

 work the same capsulated foci were found after slaughter. The author believes 

 that heavy feeding aided the curative action of this vaccine to a considerable 

 extent. 



The remaining 53 I'eacting animals were injected twice. Five were slaugh- 

 tered, and 4 of these showed calcified foci, while the fifth was macroscopically 

 free from tuberculosis. Thirteen of the living animals are in very good shape, 

 while the remainder are in a fair state of preservation. 



Diseases of the cow (excluding tuberculosis) affecting the milk in their 

 relationship to human diseases, W. G. Savage (Jour. Meat and Milk Hyg., 1 

 (1911), Nos. 4,. pp. 175-191; 5, pp. 231-24 'i)- — This article discusses the various 

 nontubercular diseases occurring in cows, such as anthrax, Gaertner infections, 

 gastro-enteritis. Malta fever, mastitis, ulcerated teats, and sore throat, with 

 particular reference to their relation to the production of disease in man by 

 way of the milk from such animals. 



A number of outbreaks are cited which had their origin fi'om the cow. 



Besearches on the etiology of cachexia aquosa of ruminants. — The role of 

 worms in gastro-intestinal strongylosis of sheep, Cuill6, Marotkl, and Pa- 

 NissET (Compt. Rend. Sac. Biol. [Paris], 10 (1911), No. I4, pp. 567, 568).— 

 The authors have determined that the disease known as cachexia aquosa, 

 which seriously affected ruminants during 1910, is not entirely dependent upon 

 the presence of the liver fiuke. In all the cachectic animals examined numerous 



