284 EXPERIMENT STATION RECORD. 



when large quantities of dead glanders bacilli were injected into the stomach of 

 jjuinea i)igs they produced more or less severe intoxication followed by a rapid 

 death in cases where large numbers of the bacilli were used. Not only the 

 soluble products of the bacilli but the bacterial bodies themselves pass through 

 the intestinal wall and are found in the ganglia, si)leen, and lungs, where they 

 may produce broncho-pneumonia. Where small (luantities of the dead bacilli 

 are used a tolerance is develoi)ed on the part of the animal, which may last for 

 a period of :> months. 



A disease of the horse simulating farcy, F. S. H. Baldrey and G. D. Mar- 

 tin {Jour. Trop. Yet. ticL, 1 (IDOG), No. 3, pp. 316-319). "^In a case which closely 

 resembled farcy an organism was obtained which is somewhat shorter and 

 thicker than that of the glanders bacillus. Inoculation of guinea pigs with this 

 organism produced a mild illness which lasted for 4 or 5 days, but the lesions 

 were not fatal. The period of incubation was 4 days. 



An anthrax-like bacillus found in a horse suspected of anthrax, R. E. 

 Montgomery {Joiiy.Trop.Vei. HcL, 1 {190(!),]\'<t. 3. pp. 2SJf-29.'f). — In a suspected 

 case of anthrax it was found impossible to ol)taiu cultures of the true anthrax 

 bacillus. The symi)toms and lesions were apparently those of anthrax. Notes 

 are given on the behavior of the organism on various cultural media. From 

 inoculation experiments it was found possible to obtain pure cultures of the 

 organism which did not produce serious disease in most cases. The exact 

 relationship of the organism is not known. 



Experimental nagana, A. Rodet and G. Vaixet {Compt. Rend. Acad. Sci. 

 [Paris], 11,3 (1906). No. 6, pp. 321, 328).— In previous experiments the authors 

 have tested the effect of injections of the spleen of dogs into rats artiticially 

 inoculated with nagana. 



Attention is called to the fact that a sudden reduction in the number of 

 l)lood parasites may take place under other conditions in which the action of 

 the spleen is excluded. It is necessary, therefore, to be rather cautious in draw- 

 ing conclusions as to the effect of inoculations of spleen. The authors are dis- 

 posed to ascribe the sudden disappearance of the blood parasites in the dog to a 

 crisis in the disease during which the trypanosomes are destroyed by the action 

 of a specific property of the blood. 



Trypanosoma hrucei and experimental nagana, A. Rodet and G. Vallet 

 (Compt. Rend. .S'oc. Biol. [Paris], 61 (1906), No. 21, pp. 186-189).— \s the result 

 of an extended study of the blood parasites of nagana in rats and dogs, the 

 authors conclude that some of the abnormal forms occasionally called ameboid 

 are not regular stages in the development of the parasite, but are the result of 

 abnormal stimulation of these organisms. 



The parasites multipl.v rapidl.v in the blood, in especially large numbers in 

 the capillaries of the liver. The blood parasites are also rapidly destroyed in 

 the infected animal, and in this destruction certain oi'gans are especially active, 

 the spleen being most so and the liver least. The trypanosomes, however, may 

 degenerate and die in the circulating blood. In most cases where secondary 

 bacterial infection took place in the experimental animals the number of 

 trypanosomes at the time of death was very small. 



Souma, L. Cazalbou (Rev. Gen. MM. Vet., 8 (1906), No. 89-90. pp. 240-2.',8).— 

 In the French Soudan a trypanosomiasis prevails among horses and cattle and 

 is commonly referred to under the name souma. It has affected a large numl)er 

 of animals during the past .3 years, attacking 14 per cent of horses and cattle 

 in certain localities. There appears to be some difference in the susceptibility 

 of different breeds of cattle. Zebus are even more susceptible than common 

 cattle. Notes are given on the symptoms and etiology of the disease. It ap- 

 pears to be carried by certain species of Tabanus. 



