VKTKRIXAIIV Sf'TKNCK. 4S1 



AITcctoil ••iiiiuinls must he (•niisi<lcn'(l ;is ;i s()in'<(' 111' iiircst.-ilioii .-md sliould hi' 

 rcmovod Irmu the rest of the llm-k. Soiiu- licnrlit is also derived t'roiii adniiiiis- 

 ti'ring a teiiic 



The microscopic changes in the nervous system in cases of chronic 

 dourine as compared with those found in sleeping sickness, F. W. ^Iott 

 (Proc. Roil. Soc. \ L>)inl(,ii\. Sfi: H. !'■■< (IHOU). \o. B522, ;>/>. / / .'. /*/.s-. /i. — In 

 chronie dourine llie uerve cells of the sijiual cord show decid(>d color cliaiii^es, 

 and th(! blood vessels exhibit e\idence of iullaiiiiuation. with small hemor- 

 rlia,:,'es. The nerve lissut' of the spinal cord becomes infiltrated with lympho- 

 cytes and all blood vessels are surroinided with small round cells. These 

 |iatholo,i;icaI conditions are compared with those which are obser\'ed in sleepinj; 

 sickness. 



The destruction of Trypanosonia brucei in the spleen, A. Rodet and G. 

 V.vi.i.ET iCojJii)!. RciKl. Acad. Sci. [l'(iris\, lJ,.i (l'.)OC,). \<>. ii. i>i>. 1229-1231).— 

 An experimental study was made of this disease in dojjs and rats. The authors 

 found that the blood i)arasites are rapidly destroyed in the spleen. In fact, 

 the spleen appears to be the most important organ in this work, although it is 

 assisted to some extent by other organs belonging to the lymphatic system. 



The treatment of trypanosomiases with benzidin colors, ^I. Xicolle and 

 1'. Mesxil (Aim. /list. Pu.^tciir. 20 (1906). Ao. 6, pp. -'//7-i',S).— Recently much 

 interest has arisen in the stud.v of the effect of various dyes upcm blood para- 

 sites, particularly those of nagana, surra, and mal de cadei'as. The authors 

 have made an elaborate study of the chemical composition and action of thirteen 

 d.ves belonging to the benzidin group. 



The authors worked with mice which were first inoculated with one or the 

 other of the diseases mentioned above and then given hyperdermic injections of 

 one per cent solution of the dyestuffs in doses of one c. c. It was found that 

 dichlorobenzidin and tolidin after one injection caused the total disappearance 

 of the blood parasites in many cases. The action of the coloring matters was 

 not the same when used in treating the three diseases. 



Diseases caused by palisade worms in horses, F. Glagk {ZtHchr. Jiifccfhnis- 

 Iraiik. u. III/!/. Ifinisticrc 1 ( I'.iOi;). \o. ,J-.7. iip. .I'/l-Slo). — A careful study was 

 made of the .nnatomical characters and biology of Sclcrdsfoiiniiii cdcutatimi and 

 S. bidciitdtinii. 



These worms in various stages are frequentl.v fomid together in the same horse 

 i>v colt, and for this reason some difficulty of identification is experienced, par- 

 ticularly in the larval stages. The author believes, however, that the 2 species 

 are distinct, and offers good evidence as a basis for that belief. The parasites 

 in question may appear in various tissues of the host, causing injury by direct 

 removal of the blood, a production of hemorrhages, and mechanical injuries. 

 l)articularly in the peritoneum. Occasionally chronic cases of general cachexia 

 .ire observed as a result of infestation with these parasites. 



Protective vaccine against rabies, O. Heli.er (Die tSchuizintpfiiiu/ (/ccjen 

 L//.s.vf/. .Jena: (Jii-stac F [.■seller. 1906. pp. I'i2). — The literature relating to rabies 

 is criticall.v dscussed in connection witli an extensive bibliograph.v which occu- 

 pies pages !>2-14L*. 



The author was chietly concerned during bis investigations in determining 

 the cause of rabies as far as possible, and in obtaining a nonvirulent vaccine. 

 As a result of these studies the conclusion is reached that rabies is not a bac- 

 terial disease. It appears that immunity to rabies may be brought about by the 

 use of the material which constitutes the organism of I'abies, together with the 

 toxic substances which are produced in auimals as a result of infection with 

 rabies. 



