155 



cocvlcs IVom tlic s|)locn frajfiiiciil slowly iiivndcd llic incdiimi 

 and reached llie nei^hlxjiirliood of (he eolony of ri])rol)lasls. 

 On Ihe i)th day. the fil)rohhisls liad heeoine very lai-f^e and 

 llieii- cylo))! isni was dark and loaded wilh Tat i«i-anides. 'I'he 

 lyniphoeyles prolileraled very actively and some of them 

 reached Ihe fi])rol)lasts. Durinff the following? days, the ap- 

 pearance ol" Ihe fibroblasts changed. They became slender 

 and elongated and theii* cytoplasm decreased in volume and 

 Ihey began to ])i"o]iferale actively, became refreshed and 

 fully active. — This is a beautiful demonstration of the 

 growth-promoting function of the leucocytes and a clean cut 

 experiment proving that leucocytes are ca])al)le of transfor- 

 ming the serum into comi)lex substances which supply fibro- 

 blasts with nutrient material for their multiplication, sub- 

 stances with are called trephoiies. 



2. TUV. PHY.SIOLOGIC.AL INTEGRITY (W 

 TIS.Sl'E CELL.S. 



It has been much discussed whetliei* the tissue cells have 

 to be considered as genetical and morphological units of 

 the organism, or if certain cell colonies or tissues or the 

 entire organism may be considered as the unit. 



The synzylium theory of the organism on the one side 

 represented by Rhode ^^o)^ and the bioblast theory (A 1 1- 

 m a n n" on the other are the extremes of Ihe numerous 

 lhe(U-ies. The •Zellenstaat'' or •Bausteintheorie" (V i r c h o w. 

 Ifaeckel: is the c(mcei)tion of the perfect disconliuuily 

 and independency of the individual tissue cells. On the con- 

 liary the ■•Synzylium" theoi'y or symblasl theory, is the 

 notion of i)erfect continuity of the plasma of the organism 

 by the means of cytoplasma bridges between the cells. These 

 bridges or anaslomotics, called ••plasmodesms". should serve 

 as itineraries for the transport of alimentary products, of 

 internal secretions and of living cyto])lasm. 



