197 



its surface shiny as a fresh mucous membrane. Macrosco- 

 pically as well as microscroi^ically it appeared as a semi- 

 Iransparent body with a sli<TlUly denser central portion. 

 Active peristaltic luovemeuts were observed around tlie edge 

 of the body as well as on the free edge of the ciilicula of 

 the epithelial cells. A lively migration of ameboid cells look 

 place between the epithelial cells. 



Active contraction of tlie intestinal muscles could be ob- 

 served even after more than a months cultivation. These 

 contractions were brought about by a slight cooling of the 

 preparation. 



The size of the bodies, or -organisms'" varied according 

 to their age. Generally, they tended to decrease in size as 

 time went on. 



The actual secretion could be seen to exude from the 

 epithelial cells. The secretion was rather mucous, and after 

 a few hours cultivation the body was floating around in a 

 little lake in the plasma clot. In subsequent stages, the in- 

 testinal body became pellucid, and the coat of regular cubic 

 epithelium could be studied thoroughly. Often it was pos- 

 sible to observe small appendicular cystic formations which 

 appeared on the surface of the body within a few hours. 

 Thcs'^ cysts increased markedly in size from hour to hour 

 and it was clearly seen, that the fluid could only pass in 

 from the exterior and not in the opposite direction. At Ihe 

 time when the cultures were to be transferred to a fresh 

 medium, the cysts were injured by the operation and col- 

 la]3sed. 



By the histological examination of the intestinal bodies 

 after a months cultivation, they were found in an excellent 

 state of preservation. The cylindrical epithelium had grown 

 all around the fragment. The villi had disappeared and the 

 surface of the body was very even and smooth. The epi- 

 thelium in the Lieberkiihn glands was well preserved 

 in many cases, but did not seem to have any communication 

 with the outside. The connective tissue cells had formed 



